{"product_id":"cheminformatics-and-bioinformatics-at-the-interface-with-systems-biology-bridging-chemistry-and-medicine-9781839161629","title":"Cheminformatics and Bioinformatics at the Interface with Systems Biology: Bridging Chemistry and Medicine","description":"\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cblockquote\u003eDrug development is becoming increasingly expensive, while the number of approved drugs is decreasing. This is a problem for the pharmaceutical industry and for those suffering from diseases with no or few available treatments. Advances in computational chemistry, computer science, structural biology, and molecular biology have contributed to improved drug design strategies and reduced the time taken for drug discovery. By integrating drug design approaches with systems biology, we can create a powerful tool for understanding the mechanisms of patho-physiological systems and identifying lead molecules for various diseases. This integration can also improve safety and efficacy and lead to better approval rates. \u003c\/blockquote\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFormat\u003c\/strong\u003e: Hardback\u003cbr\u003e\u003cstrong\u003eLength\u003c\/strong\u003e: 264 pages\u003cbr\u003e\u003cstrong\u003ePublication date\u003c\/strong\u003e: 08 September 2023\u003cbr\u003e\u003cstrong\u003ePublisher\u003c\/strong\u003e: Royal Society of Chemistry\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003eThe cost of drug development is on the rise, while investment returns are dwindling. The number of drugs approved by the FDA is decreasing in terms of the number of new molecular entities (NMEs). Several reasons have been cited for this decline, including adverse side effects and reduced efficiency of potential compounds. This poses a significant problem for both the pharmaceutical industry and individuals suffering from diseases with limited or no available treatments.\u003cbr\u003e\u003cbr\u003eAdvances in computational chemistry, computer science, structural biology, and molecular biology have played a pivotal role in improving drug design strategies and reducing the time taken for drug discovery. By integrating cheminformatics and bioinformatics with systems biology, we can gain a deeper understanding of the mechanisms of patho-physiological systems and identify lead molecules for various diseases. This integration of drug design approaches can also play a crucial role in predicting and rationalizing drug effects and side effects, enhancing safety and efficacy, and ultimately leading to better approval rates.\u003cbr\u003e\u003cbr\u003eAddressing the lack of knowledge on the fundamental aspects of computational tools for drug discovery, this book serves as a compilation of recent bioinformatics and cheminformatics approaches, along with their integration with systems biology. Primarily aimed at researchers and academics in chem- and bioinformatics, it can also be a valuable resource for advanced-level students.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWeight\u003c\/strong\u003e: 540g\u003cbr\u003e\u003cstrong\u003eDimension\u003c\/strong\u003e: 234 x 156 (mm)\u003cbr\u003e\u003cstrong\u003eISBN-13\u003c\/strong\u003e: 9781839161629\u003c\/p\u003e","brand":"Aman ChandraKaushik,AamirMehmood,DongqingWei,SadiaNawab,ShaktiSahi,AjayKumar","offers":[{"title":"Hardback","offer_id":44572897607930,"sku":"9781839161629","price":151.37,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0522\/4297\/2845\/products\/1694798200542_book.jpg?v=1695055937","url":"https:\/\/shulphink.com\/products\/cheminformatics-and-bioinformatics-at-the-interface-with-systems-biology-bridging-chemistry-and-medicine-9781839161629","provider":"Shulph Ink","version":"1.0","type":"link"}