{"product_id":"contemporary-accounts-in-drug-discovery-and-development-9781119627715","title":"Contemporary Accounts in Drug Discovery and Development","description":"\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cblockquote\u003e\n\u003cbr\u003eDrug discovery is a lengthy and complex process that requires knowledge of chemistry and biology, as well as experience. Contemporary Accounts in Drug Discovery and Development provides drug discovery scientists with the knowledge they need to quickly gain mastery of the process, including pharmacology, drug metabolism, biology, drug development, and clinical studies. It also includes case histories, biological rationales, drug design principles, SAR development, ADMET considerations, and clinical studies. \u003c\/blockquote\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFormat\u003c\/strong\u003e: Hardback\u003cbr\u003e\u003cstrong\u003eLength\u003c\/strong\u003e: 480 pages\u003cbr\u003e\u003cstrong\u003ePublication date\u003c\/strong\u003e: 29 April 2022\u003cbr\u003e\u003cstrong\u003ePublisher\u003c\/strong\u003e: John Wiley and Sons Ltd\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003eDrug discovery is a rigorous and intricate journey that often spans several years, requiring a deep understanding of chemistry and biology. It begins with identifying an unmet medical need and then determining a biological target that can be targeted with a drug. This is followed by a painstaking process of screening a vast chemical library to identify potential leads, which are then subjected to chemical optimization to enhance their efficacy and safety. Preclinical studies and clinical trials are then conducted to evaluate the effectiveness and safety of the candidate drugs in humans.\u003cbr\u003e\u003cbr\u003eThe success rate of drug discovery and development is crucial for advancing the field of medicine. By staying up-to-date with the latest principles and technologies, scientists can improve their chances of discovering new treatments that can improve the lives of patients.\u003cbr\u003e\u003cbr\u003eContemporary Accounts in Drug Discovery and Development is a valuable resource for medicinal chemists and pharmaceutical scientists who want to gain a comprehensive understanding of the drug discovery process. The book provides detailed accounts of each drug covered, including pharmacology, drug metabolism, biology, drug development, and clinical studies. Modern drug discovery principles and technologies are integrated throughout, making it an essential tool for anyone working in the field.\u003cbr\u003e\u003cbr\u003eIn addition to providing a comprehensive overview of the drug discovery process, the book also includes case histories that serve as an engaging way of learning about the challenges and successes of drug discovery. These case histories provide valuable insights into the decision-making processes and strategies used by scientists, as well as the ethical considerations that are involved in the development of new drugs.\u003cbr\u003e\u003cbr\u003eFurthermore, the book offers detailed biological rationales and background information on each drug, as well as drug design principles, SAR development, ADMET considerations, and clinical studies. This information is invaluable for scientists who are working on developing new drugs, as it helps them to understand the potential risks and benefits of their compounds.\u003cbr\u003e\u003cbr\u003eThe book also provides a comprehensive history of individual marketed small molecule drugs, as well as coverage of drug candidates that have passed Phase I clinical trials with different modalities, such as antibody drug conjugates (ADC), proteolysis-targeting chimera (PROTAC), and peptide drugs. This information is particularly useful for researchers and pharmaceutical companies who are exploring new drug development strategies.\u003cbr\u003e\u003cbr\u003eFinally, the book discusses the application of new technologies in drug discovery, such as high-throughput screening, virtual screening, and machine learning. These technologies have revolutionized the drug discovery process, allowing scientists to identify potential leads more efficiently and effectively.\u003cbr\u003e\u003cbr\u003eIn conclusion, Contemporary Accounts in Drug Discovery and Development is a must-read for anyone who wants to gain a deeper understanding of the drug discovery process. The book provides a comprehensive overview of the field, including pharmacology, drug metabolism, biology, drug development, and clinical studies. It also includes case histories, biological rationales, drug design principles, SAR development, ADMET considerations, and clinical studies. Additionally, the book discusses the application of new technologies in drug discovery, making it an essential resource for researchers and pharmaceutical companies. By staying up-to-date with the latest principles and technologies, scientists can improve their chances of discovering new treatments that can improve the lives of patients.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWeight\u003c\/strong\u003e: 1040g\u003cbr\u003e\u003cstrong\u003eDimension\u003c\/strong\u003e: 189 x 265 x 34 (mm)\u003cbr\u003e\u003cstrong\u003eISBN-13\u003c\/strong\u003e: 9781119627715\u003c\/p\u003e","brand":"X Huang","offers":[{"title":"Hardback","offer_id":44106058137850,"sku":"9781119627715","price":87.26,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0522\/4297\/2845\/products\/1652441015022_book.jpg?v=1652521537","url":"https:\/\/shulphink.com\/products\/contemporary-accounts-in-drug-discovery-and-development-9781119627715","provider":"Shulph Ink","version":"1.0","type":"link"}