{"product_id":"myeloidderived-suppressor-cells-9780443218071","title":"Myeloid-Derived Suppressor Cells","description":"\u003cp\u003e\u003c\/p\u003e\u003cblockquote\u003eMyeloid-Derived Suppressor Cells,Volume 184 in the Methods in Cell Biology series, includes comprehensive protocols to assess the role of MDSCs in a variety of diseases. The volume covers the Detection, Isolation, and Immunomodulatory Functions of MDSCs, as well as other chapters on their differentiation, dissemination, and immunosuppressive functions. \u003c\/blockquote\u003e\u003cp\u003e\u003cstrong\u003eFormat\u003c\/strong\u003e: Hardback\u003cbr\u003e\u003cstrong\u003eLength\u003c\/strong\u003e: 318 pages\u003cbr\u003e\u003cstrong\u003ePublication date\u003c\/strong\u003e: 22 March 2024\u003cbr\u003e\u003cstrong\u003ePublisher\u003c\/strong\u003e: Elsevier Science Publishing Co Inc\u003cbr\u003e\u003c\/p\u003e \u003cp\u003e\u003cbr\u003eThe Methods in Cell Biology series, Volume 184, presents comprehensive protocols to investigate the role of myeloid-derived suppressor cells (MDSCs), an immature and heterogeneous cell population originating from the myeloid lineage, known for their potent immunosuppressive activity in various diseases. This volume offers a range of intriguing protocols, including:\u003cbr\u003e\u003cbr\u003e• Detection of myeloid-derived suppressor cells by flow cytometry.\u003cbr\u003e• Determination of murine myeloid-derived suppressor cells by flow cytometry.\u003cbr\u003e• Isolation of Myeloid-Derived Suppressor Cells (MDSCs) from Endometriotic Mice Model and their Immunomodulatory Functions.\u003cbr\u003e• Simple protocol for measuring CD11b+ GR-1+ (Ly6C+\/Ly6G+) myeloid cells from a minimum volume of mouse peripheral blood.\u003cbr\u003e• Additional chapters covering Assessment of myeloid-derived suppressor cell differentiation ex vivo.\u003cbr\u003e• Single clonal tracking on biomimetic microtextured platforms for real-time guided migration analysis of myeloid-derived suppressor cell dissemination characteristics ex vivo.\u003cbr\u003e• Isolation and immunosuppressive functions of myeloid-derived suppressor cell-derived exosomes.\u003cbr\u003e• Characterization of lysosomal acid lipase in Ly6G+ and CD11c+ myeloid-derived suppressor cells.\u003cbr\u003e• In Vitro Osteoclastogenesis Assessment using Murine Myeloid-Derived Suppressor Cells.\u003cbr\u003e• Estimating Nitric Oxide (NO) from MDSCs by Griess Method.\u003cbr\u003e• In vitro generation of myeloid-derived suppressor cells (MDSCs) from hematopoietic progenitor cells (HPCs).\u003cbr\u003e\u003cbr\u003eThese protocols provide valuable tools for researchers seeking to understand the dynamics and functions of MDSCs in disease contexts. By employing these methods, scientists can gain insights into the role of MDSCs in immune suppression, tumor progression, and other pathological conditions, leading to potential therapeutic interventions.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWeight\u003c\/strong\u003e: 450g\u003cbr\u003e\u003cstrong\u003eDimension\u003c\/strong\u003e: 234 x 191 (mm)\u003cbr\u003e\u003cstrong\u003eISBN-13\u003c\/strong\u003e: 9780443218071\u003c\/p\u003e","brand":"Shulph Ink","offers":[{"title":"Hardback","offer_id":45391757607162,"sku":"9780443218071","price":153.87,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0522\/4297\/2845\/files\/1711135137992_book.jpg?v=1711271256","url":"https:\/\/shulphink.com\/products\/myeloidderived-suppressor-cells-9780443218071","provider":"Shulph Ink","version":"1.0","type":"link"}