{"product_id":"natural-killer-nk-cells-methods-and-protocols-9781071621622","title":"Natural Killer (NK) Cells: Methods and Protocols","description":"\u003cp\u003e\u003c\/p\u003e\u003cblockquote\u003eThis detailed book provides a broad collection of methodologies for natural killer (NK) cell research, including isolation, differentiation, functional tests, and clinical applications. Written for the Methods in Molecular Biology series, it is an ideal guide for researchers looking to contribute to the further development of NK cell research. \u003c\/blockquote\u003e\u003cp\u003e\u003cstrong\u003eFormat\u003c\/strong\u003e: Paperback \/ softback\u003cbr\u003e\u003cstrong\u003eLength\u003c\/strong\u003e: 330 pages\u003cbr\u003e\u003cstrong\u003ePublication date\u003c\/strong\u003e: 30 March 2023\u003cbr\u003e\u003cstrong\u003ePublisher\u003c\/strong\u003e: Springer-Verlag New York Inc.\u003cbr\u003e\u003c\/p\u003e \u003cp\u003e\u003cbr\u003eThis comprehensive book offers a diverse range of methodologies for studying natural killer (NK) cells. It begins by providing various techniques for isolating and differentiating NK cells, followed by comprehensive functional tests, including cytotoxicity, viral infection, and metabolism assays. Additionally, the volume explores the clinical applications of NK cells, offering insights into their potential therapeutic roles in various diseases. Written in the esteemed Methods in Molecular Biology series, each chapter includes an introduction, a list of necessary materials and reagents, step-by-step laboratory protocols, and helpful tips on troubleshooting and avoiding common pitfalls. Authored by esteemed experts in the field, Natural Killer (NK) Cells: Methods and Protocols serves as an invaluable resource for researchers seeking to advance their understanding of NK cell research, both at the basic and clinical levels.\u003cbr\u003e\u003cbr\u003eIsolation and Differentiation of NK Cells:\u003cbr\u003eThe book begins by discussing the methods for isolating and differentiating NK cells from peripheral blood and other tissues. These techniques include cell sorting, flow cytometry, and immunomagnetic separation. The authors provide detailed protocols for each step, including the use of specific antibodies and reagents to enrich and isolate NK cells.\u003cbr\u003e\u003cbr\u003eFunctional Tests:\u003cbr\u003eThe next section focuses on functional tests that can be performed on NK cells. These tests include cytotoxicity assays, which measure the ability of NK cells to kill target cells, and viral infection assays, which assess their antiviral response. Metabolism assays are also discussed, which help in understanding the metabolic pathways of NK cells and their role in immune regulation.\u003cbr\u003e\u003cbr\u003eClinical Applications:\u003cbr\u003eThe book explores the clinical applications of NK cells in various diseases, such as cancer, autoimmune disorders, and infectious diseases. The authors discuss the role of NK cells in immune surveillance and their potential use as therapeutic agents in these conditions. They also provide insights into the development of NK cell-based therapies and the challenges associated with their implementation.\u003cbr\u003e\u003cbr\u003eConclusion:\u003cbr\u003eNatural Killer (NK) Cells: Methods and Protocols is a comprehensive and authoritative guide for researchers interested in studying NK cells. The book offers a diverse range of methodologies, from isolation and differentiation to functional tests and clinical applications. Written in a clear and concise manner, the book is accessible to researchers with varying levels of expertise. With its practical approach, it serves as an ideal resource for researchers looking to contribute to the further development of basic and clinical NK cell research.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWeight\u003c\/strong\u003e: 655g\u003cbr\u003e\u003cstrong\u003eDimension\u003c\/strong\u003e: 254 x 178 (mm)\u003cbr\u003e\u003cstrong\u003eISBN-13\u003c\/strong\u003e: 9781071621622\u003cbr\u003e \u003cstrong\u003eEdition number\u003c\/strong\u003e: 1st ed. 2022\u003c\/p\u003e","brand":"Shulph Ink","offers":[{"title":"Paperback \/ softback","offer_id":44307627802874,"sku":"9781071621622","price":116.61,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0522\/4297\/2845\/products\/noImage_1_4b2ec988-8971-4245-8fac-40e9a20883fb.jpg?v=1688110629","url":"https:\/\/shulphink.com\/products\/natural-killer-nk-cells-methods-and-protocols-9781071621622","provider":"Shulph Ink","version":"1.0","type":"link"}