{"product_id":"single-nucleotide-polymorphisms-human-variation-and-a-coming-revolution-in-biology-and-medicine-9783031056147","title":"Single Nucleotide Polymorphisms: Human Variation and a Coming Revolution in Biology and Medicine","description":"\u003cp\u003e\u003c\/p\u003e\u003cblockquote\u003e\n\u003cbr\u003eThis book explores the importance of Single Nucleotide Polymorphisms (SNPs) in biomedical research, which has provided a detailed understanding of evolutionary forces and how they shape human variation. It also covers the role of SNPs in human disease, personalized medicine, and mechanisms by which synonymous mutations affect protein levels. \u003c\/blockquote\u003e\u003cp\u003e\u003cstrong\u003eFormat\u003c\/strong\u003e: Hardback\u003cbr\u003e\u003cstrong\u003eLength\u003c\/strong\u003e: 234 pages\u003cbr\u003e\u003cstrong\u003ePublication date\u003c\/strong\u003e: 10 August 2022\u003cbr\u003e\u003cstrong\u003ePublisher\u003c\/strong\u003e: Springer International Publishing AG\u003cbr\u003e\u003c\/p\u003e \u003cp\u003e\u003cbr\u003eThis book delves into the significance of Single Nucleotide Polymorphisms (SNPs) in biomedical research. The evolution of SNP technologies, from labor-intensive and expensive to relatively inexpensive methods, has led to a surge in SNP discovery. In the realm of human biology, this research, particularly since the completion of the Human Genome Project, has provided a comprehensive understanding of the evolutionary forces that have generated SNPs and their impact on human variation. The ability to generate and analyze vast amounts of genetic data at a low cost holds the potential to revolutionize our understanding of human evolution and biology.\u003cbr\u003e\u003cbr\u003e\"Single Nucleotide Polymorphisms\" offers a comprehensive survey of SNPs, covering their classification into synonymous and non-synonymous variants, their role in human disease, case studies highlighting specific examples of synonymous and non-synonymous SNPs associated with human diseases or influencing therapeutic interventions, mechanisms by which synonymous mutations affect protein levels and folding, impacting human physiology and response to therapy, and the role of SNPs in personalized medicine. Understanding the origins and mechanisms of SNPs is crucial for an expanding audience. This research has the potential to transform the future of medicine. Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.\u003cbr\u003e\u003cbr\u003eSNPs Ability to Influence Disease Risk: Breaking the Silence on Synonymous Mutations in Cancer is also available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWeight\u003c\/strong\u003e: 547g\u003cbr\u003e\u003cstrong\u003eDimension\u003c\/strong\u003e: 235 x 155 (mm)\u003cbr\u003e\u003cstrong\u003eISBN-13\u003c\/strong\u003e: 9783031056147\u003cbr\u003e \u003cstrong\u003eEdition number\u003c\/strong\u003e: 1st ed. 2022\u003c\/p\u003e","brand":"Shulph Ink","offers":[{"title":"Hardback","offer_id":44103274955002,"sku":"9783031056147","price":108.28,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0522\/4297\/2845\/products\/noImage_1_d17971da-8a65-4d39-ad3b-3d9d8fc42922.jpg?v=1669751377","url":"https:\/\/shulphink.com\/products\/single-nucleotide-polymorphisms-human-variation-and-a-coming-revolution-in-biology-and-medicine-9783031056147","provider":"Shulph Ink","version":"1.0","type":"link"}