{"product_id":"techniques-for-downstream-process-for-biologic-drugs-and-vaccines-9780443191572","title":"Techniques for Downstream process for Biologic Drugs and Vaccines","description":"\u003cp\u003e\u003c\/p\u003e\u003cblockquote\u003e\n\u003cbr\u003eDownstream process for Biologic Drugs and Vaccines is a comprehensive resource that explains the technologies involved in processing postharvest broth to separate the target biological therapeutic products from extracellular or intercellular aspects. It covers the most important aspects of biomass processing technologies and their applications in new projects related to the development and manufacturing of therapeutic bio-products. \u003c\/blockquote\u003e\u003cp\u003e\u003cstrong\u003eFormat\u003c\/strong\u003e: Paperback \/ softback\u003cbr\u003e\u003cstrong\u003eLength\u003c\/strong\u003e: 278 pages\u003cbr\u003e\u003cstrong\u003ePublication date\u003c\/strong\u003e: 03 August 2023\u003cbr\u003e\u003cstrong\u003ePublisher\u003c\/strong\u003e: Elsevier Science Publishing Co Inc\u003cbr\u003e\u003c\/p\u003e \u003cp\u003e\u003cbr\u003eBiologic Drugs and Vaccines: Downstream Process Techniques\u003cbr\u003e\u003cbr\u003eBiologic drugs and vaccines, derived from living organisms, hold immense potential for treating various diseases. However, the production of these therapeutic products involves complex downstream processes that require specialized technologies. In this comprehensive resource, we delve into the techniques involved in processing postharvest broth to separate the target biological therapeutic products from extracellular or intercellular aspects in nature. Our goal is to achieve the highest purification form of these products, making them acceptable to end users.\u003cbr\u003e\u003cbr\u003eThe post-harvesting of fermented broth is a crucial step in the production of biologic drugs and vaccines. This process involves a series of steps, including biomass processing, extraction, and purification. Biomass processing technologies play a vital role in converting raw materials into usable forms, such as liquid or solid biomass. These technologies include methods such as hydrolysis, fermentation, and solid-state fermentation, which help to break down complex organic matter into simpler compounds that can be further processed.\u003cbr\u003e\u003cbr\u003eExtraction is another critical step in the downstream process. It involves the isolation of specific compounds or proteins from the fermented broth. Various extraction techniques, such as solid-phase extraction, liquid-phase extraction, and chromatography, are employed to achieve this. These techniques utilize different solvents, resins, and separation mechanisms to selectively extract the desired compounds from the mixture.\u003cbr\u003e\u003cbr\u003ePurification is the final step in the downstream process. It involves the removal of impurities, contaminants, and unwanted components from the extracted compounds or proteins. Purification techniques include methods such as ultrafiltration, diafiltration, and chromatography, which use different filters, membranes, and separation mechanisms to achieve high purity and specificity.\u003cbr\u003e\u003cbr\u003eIn addition to these core techniques, downstream processing of biologic drugs and vaccines also involves other important aspects, such as quality control, stability testing, and formulation. Quality control measures ensure that the final products meet stringent quality standards and specifications. Stability testing is conducted to evaluate the long-term storage and shelf life of the products. Formulation involves the development of appropriate dosage forms and delivery systems for the final products.\u003cbr\u003e\u003cbr\u003eThis comprehensive resource is designed to help non-engineering students and scientists easily capture the basic principle of biomass processing technologies and their applications in new projects related to the development and manufacturing of therapeutic bio-products. As the field of biotechnology continues to evolve, with the integration of medical sciences, physical sciences, and engineering, the need for the development of microbial or cell line process technology and application for large-scale isolation and purification of metabolites or vaccines through the fermentation process has become increasingly significant. This book covers the most important aspects of these technologies, providing a valuable resource for researchers, scientists, and industry professionals alike.\u003cbr\u003e\u003cbr\u003eIn conclusion, the downstream process techniques for biologic drugs and vaccines are crucial in the production of these therapeutic products. These techniques involve a series of steps, including biomass processing, extraction, and purification, to achieve the highest purification form of the target biological therapeutic products. With the integration of medical sciences.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWeight\u003c\/strong\u003e: 596g\u003cbr\u003e\u003cstrong\u003eDimension\u003c\/strong\u003e: 191 x 236 x 18 (mm)\u003cbr\u003e\u003cstrong\u003eISBN-13\u003c\/strong\u003e: 9780443191572\u003c\/p\u003e","brand":"Basanta KumaraBehera","offers":[{"title":"Paperback \/ softback","offer_id":44523026088186,"sku":"9780443191572","price":123.62,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0522\/4297\/2845\/products\/1692979737593_book.jpg?v=1693206709","url":"https:\/\/shulphink.com\/products\/techniques-for-downstream-process-for-biologic-drugs-and-vaccines-9780443191572","provider":"Shulph Ink","version":"1.0","type":"link"}