{"product_id":"the-chemical-biology-of-thrombin-9781138055902","title":"The Chemical Biology of Thrombin","description":"\u003cp\u003e\u003c\/p\u003e\u003cblockquote\u003e\n\u003cbr\u003eThrombin, a regulatory protease, has been extensively studied due to its availability in highly purified form. This book covers the discovery of thrombin by Andrew Buchanan in 1842 to the present, with a focus on research conducted by the author and his colleagues. It discusses the purification of thrombin, the role of exosites in thrombin function, and the development of an oral inhibitor for thrombosis. \u003c\/blockquote\u003e\u003cp\u003e\u003cstrong\u003eFormat\u003c\/strong\u003e: Hardback\u003cbr\u003e\u003cstrong\u003eLength\u003c\/strong\u003e: 268 pages\u003cbr\u003e\u003cstrong\u003ePublication date\u003c\/strong\u003e: 02 May 2022\u003cbr\u003e\u003cstrong\u003ePublisher\u003c\/strong\u003e: Taylor \u0026amp; Francis Ltd\u003cbr\u003e\u003c\/p\u003e \u003cp\u003e\u003cbr\u003eThis book is a thorough examination of thrombin, particularly in its role as a regulatory protease. The availability of highly purified thrombin has facilitated rapid advancements in our understanding of this crucial macromolecule in cell biology. The text primarily concentrates on research findings from the discovery of thrombin by Andrew Buchanan in 1842 to the present day. The author and his colleagues have conducted substantial research in this field. The author's pioneering work on thrombin purification laid the foundation for much subsequent research on the molecule. This volume serves as a framework for future studies, made possible by the discovery of the significance of exosites in thrombin function.\u003cbr\u003e\u003cbr\u003eThe current work presents the development of an oral inhibitor of thrombin for the prevention of thrombosis.\u003cbr\u003e\u003cbr\u003eKey Features:\u003cbr\u003e\u003cbr\u003eReviews the history of Thrombin (Fibrin Ferment)\u003cbr\u003e\u003cbr\u003eDocuments the relation of protein engineering and chemical modification in the study of thrombin\u003cbr\u003e\u003cbr\u003eSummarizes the interaction of thrombin with fibrinogen and fibrin\u003cbr\u003e\u003cbr\u003eOutlines the role of exosites in thrombin function\u003cbr\u003e\u003cbr\u003eDescribes the development of an oral inhibitor for thrombin\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWeight\u003c\/strong\u003e: 570g\u003cbr\u003e\u003cstrong\u003eDimension\u003c\/strong\u003e: 162 x 241 x 24 (mm)\u003cbr\u003e\u003cstrong\u003eISBN-13\u003c\/strong\u003e: 9781138055902\u003c\/p\u003e","brand":"Roger L. Lundblad","offers":[{"title":"Hardback","offer_id":44103946961146,"sku":"9781138055902","price":147.56,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0522\/4297\/2845\/products\/1651832979159_book.jpg?v=1651901571","url":"https:\/\/shulphink.com\/products\/the-chemical-biology-of-thrombin-9781138055902","provider":"Shulph Ink","version":"1.0","type":"link"}