A Case-Based Guide to Clinical Endocrinology

A Case-Based Guide to Clinical Endocrinology, Third Edition emphasizes the latest investigative advances in imaging and molecular diagnostics and new treatment approaches for common and complex endocrine conditions. It includes case histories written by experts and covers the APDEM curriculum.

Format: Paperback / softback
Length: 560 pages
Publication date: 06 January 2023
Publisher: Springer Nature Switzerland AG

Now in a revised and expanded third edition, this case-based guide emphasizes the latest investigative advances in both imaging and molecular diagnostics and new treatment approaches for a wide variety of common and complex endocrine conditions. Utilizing unique clinical case histories, each main endocrine condition and disorder is curated by a senior Section Editor with an introduction to his or her area covering both physiology and pathophysiology. This introductory chapter is followed by a number of case histories written by invited experts and designed to cover the important relevant pathophysiology, following a consistent chapter format for ease of use, including bulleted objectives, case presentations, review of the diagnosis, lessons learned, and 3-5 multiple-choice review questions. Section headings include the pituitary, thyroid (overactivity, underactivity, and cancer), parathyroid, adrenal disorders, metabolic bone disease, type 2 diabetes, lipid abnormalities, obesity, and pregnancy. Topics new to this edition include PCOS, transgender medicine, and the endocrine effects of viral infections. With a focus on covering major parts of the APDEM curriculum, A Case-Based Guide to Clinical Endocrinology remains a tremendous resource for junior and veteran clinicians alike.

The endocrine system is a complex network of glands and organs that produce and release hormones to regulate various bodily functions, including metabolism, growth and development, reproduction, and mood. Endocrine disorders can arise when there is an imbalance in hormone production or secretion, leading to a range of symptoms and complications.

One of the most common endocrine disorders is diabetes, which occurs when the body either does not produce enough insulin or does not use it effectively. Insulin is a hormone that regulates blood sugar levels, and when it is not produced in sufficient amounts, blood sugar levels can rise to dangerous levels, leading to a range of health problems, including heart disease, kidney disease, and vision loss.

Another endocrine disorder is thyroid disease, which occurs when the thyroid gland produces too much or too little thyroid hormone. Thyroid hormone plays a crucial role in metabolism, and when it is not produced in the correct amounts, it can lead to a range of symptoms, including weight gain, fatigue, and mood swings.

Parathyroid disease is a condition that occurs when the parathyroid glands produce too much parathyroid hormone, which can lead to high blood calcium levels, which can cause bone weakness, muscle cramps, and kidney stones.

Adrenal disorders include conditions such as Addison's disease, Cushing's disease, and adrenal insufficiency, which occur when the adrenal glands produce too little or too much cortisol, aldosterone, or adrenaline. Cortisol is a hormone that regulates blood pressure and blood sugar levels, while aldosterone regulates salt and water balance, and adrenaline is a hormone that is released in response to stress.

Metabolic bone disease is a condition that occurs when the body does not produce enough calcium or vitamin D, which can lead to bone loss and osteoporosis. Osteoporosis is a condition in which bones become weak and brittle, making them more susceptible to fractures.

Lipid abnormalities include conditions such as high cholesterol, high triglycerides, and low HDL (good) cholesterol, which can increase the risk of heart disease and stroke. High cholesterol can be caused by a diet high in saturated and trans fats, while high triglycerides can be caused by a diet high in sugar and refined carbohydrates. Low HDL cholesterol can be caused by a diet high in saturated and trans fats and low in omega-3 fatty acids.

Obesity is a condition in which excess body fat accumulates, leading to a range of health problems, including heart disease, diabetes, and joint problems. Obesity can be caused by a combination of genetic, environmental, and behavioral factors, including a diet high in saturated and trans fats, a lack of physical activity, and genetic predisposition.

Pregnancy is a period of significant hormonal changes that can lead to a range of symptoms and complications, including gestational diabetes, preeclampsia, and postpartum depression. Gestational diabetes occurs when pregnant women develop high blood sugar levels, while preeclampsia is a condition that occurs when pregnant women develop high blood pressure and protein in their urine. Postpartum depression is a condition that occurs in some women after giving birth, and is characterized by mood swings, depression, and anxiety.

Treatment for endocrine disorders varies depending on the specific condition and its severity. For example, treatment for diabetes may include insulin therapy, oral medications, or lifestyle changes such as diet and exercise. Treatment for thyroid disease may include thyroid hormone replacement therapy, radioactive iodine therapy, or surgery. Treatment for parathyroid disease may include surgery to remove excess parathyroid glands or medication to regulate blood calcium levels.

In addition to treatment, lifestyle changes such as a healthy diet, regular exercise, and stress management can also help manage endocrine disorders and improve overall health. It is important to seek medical attention if you are experiencing symptoms of an endocrine disorder, as early diagnosis and treatment can help prevent complications and improve quality of life.

In conclusion, the endocrine system is a complex network of glands and organs that play a crucial role in regulating various bodily functions. Endocrine disorders can arise when there is an imbalance in hormone production or secretion, leading to a range of symptoms and complications. Treatment for endocrine disorders varies depending on the specific condition and its severity, but lifestyle changes such as a healthy diet, regular exercise, and stress management can also help manage these conditions and improve overall health. It is important to seek medical attention if you are experiencing symptoms of an endocrine disorder, as early diagnosis and treatment can help prevent complications and improve quality of life.

Weight: 878g
Dimension: 235 x 155 (mm)
ISBN-13: 9783030843694
Edition number: 3rd ed. 2022