Acute-on-Chronic Liver Failure, An Issue of Clinics in Liver Disease

Dr. Nikolaos T. Pyrsopoulos, a guest editor, highlights the importance of acute-on-chronic liver failure (ACLF), which affects up to one in four patients with cirrhosis and has a high mortality rate. This issue provides comprehensive coverage of critical clinical interventions, early recognition, and management strategies, with 17 practice-oriented topics and in-depth clinical reviews.

Format: Hardback
Length: 240 pages
Publication date: 30 June 2023
Publisher: Elsevier - Health Sciences Division

Dr. Nikolaos T. Pyrsopoulos, a renowned expert in the field of liver disease, takes the helm as guest editor for this issue of Clinics in Liver Disease, delving into the critical topic of Acute-on-Chronic Liver Failure (ACLF). Recent studies have revealed an alarming statistic: as many as one in four patients with cirrhosis succumb to ACLF, with a staggering 25% passing away within a month. This issue, dedicated solely to this important subject, offers comprehensive coverage of critical clinical interventions, encompassing diagnosis, treatment, and management. It also emphasizes the significance of early recognition of ACLF, as it lays the foundation for initiating aggressive management and, ultimately, saving lives.

Spanning 17 practice-oriented topics, this issue delves into the intricate mechanisms of ACLF, exploring its multisystemic involvement and clinical manifestations. It provides a comprehensive overview of ACLF management, encompassing strategies to optimize donor potential for patients awaiting liver transplant. Additionally, it explores future approaches and therapeutic modalities for ACLF, offering valuable insights for clinical practice.

In-depth clinical reviews are presented, offering actionable insights for clinicians. Expert authors have synthesized and distilled the latest research and practice guidelines to create clinically significant, topic-based reviews. These reviews provide a comprehensive understanding of the latest developments in ACLF, enabling practitioners to stay abreast of the most effective treatment approaches and patient care strategies.

As a timely and focused publication, Clinics in Liver Disease serves as a valuable resource for hepatologists, gastroenterologists, and healthcare professionals seeking to enhance their knowledge and expertise in the field of ACLF. Under the guidance of experienced editors, this issue continues to uphold the journal's commitment to delivering high-quality, evidence-based content that impacts clinical practice and patient outcomes.

Weight: 450g
Dimension: 229 x 151 (mm)
ISBN-13: 9780323940337