Advances in Carbohydrate Chemistry and Biochemistry

Advancements in Carbohydrate Chemistry and Biochemistry,Volume 80, presents interesting chapters on various topics, including Vinyl Sulfone-Modified Carbohydrates, Enantiomerically Pure Carbocycles, and Heterocycles, and a Biographical Memoire for Leslie Hough.

Format: Hardback
Length: 192 pages
Publication date: 08 December 2021
Publisher: Elsevier Science Publishing Co Inc

Here is the rephrased text:

Advances in Carbohydrate Chemistry and Biochemistry,Volume 80, presents a comprehensive overview of the latest developments in this field. This new volume offers a diverse range of captivating chapters, covering various topics such as Vinyl Sulfone-Modified Carbohydrates: Michael Acceptors and 2p Partners for the Synthesis of Functionalized Sugars, Enantiomerically Pure Carbocycles and Heterocycles, and a Biographical Memoire for Leslie Hough.

Vinyl Sulfone-Modified Carbohydrates: Michael Acceptors and 2p Partners for the Synthesis of Functionalized Sugars

Chapter 1: Introduction
Carbohydrates, as versatile building blocks of life, have attracted significant attention in various scientific disciplines. One area of particular interest is the modification of carbohydrates with functional groups, which can enhance their properties and applications. Vinyl sulfone (VS) is a promising moiety for such modifications, as it provides a versatile platform for the synthesis of various functionalized sugars.

Chapter 2: Vinyl Sulfone-Modified Carbohydrates as Michael Acceptors
Michael acceptors are crucial components in organic synthesis, as they play a vital role in the formation of carbon-carbon bonds. Vinyl sulfone-modified carbohydrates have emerged as promising candidates for Michael acceptors due to their unique properties. This chapter discusses the synthesis and characterization of vinyl sulfone-modified carbohydrates as Michael acceptors, including their reactivity, selectivity, and stability.

Chapter 3: Vinyl Sulfone-Modified Carbohydrates as 2p Partners
In addition to their use as Michael acceptors, vinyl sulfone-modified carbohydrates can also serve as 2p partners in various reactions. This chapter explores the synthesis and characterization of vinyl sulfone-modified carbohydrates as 2p partners, including their reactivity, selectivity, and stereoselectivity.

Chapter 4: Applications of Vinyl Sulfone-Modified Carbohydrates
The applications of vinyl sulfone-modified carbohydrates are diverse and wide-ranging. This chapter discusses the use of these compounds in the synthesis of functionalized sugars, pharmaceuticals, materials, and other important compounds.

Enantiomerically Pure Carbocycles and Heterocycles

Chapter 5: Introduction
Carbohydrates are not only important in organic synthesis but also in medicinal chemistry. Enantiomerically pure carbocycles and heterocycles are important building blocks in the synthesis of various pharmaceuticals and bioactive compounds. This chapter discusses the synthesis and characterization of enantiomerically pure carbocycles and heterocycles, including their biological activities and potential applications.

Chapter 6: Synthesis and Characterization of Enantiomerically Pure Carbocycles
Enantiomerically pure carbocycles are synthesized using various methods, including asymmetric synthesis, resolution, and chiral auxiliaries. This chapter provides an overview of these methods and highlights the key steps involved in the synthesis of enantiomerically pure carbocycles.

Chapter 7: Synthesis and Characterization of Enantiomerically Pure Heterocycles
Enantiomerically pure heterocycles are also synthesized using various methods, including asymmetric synthesis, resolution, and chiral auxiliaries. This chapter provides an overview of these methods and highlights the key steps involved in the synthesis of enantiomerically pure heterocycles.

Chapter 8: Applications of Enantiomerically Pure Carbocycles and Heterocycles
Enantiomerically pure carbocycles and heterocycles have numerous applications in medicinal chemistry, including the synthesis of various pharmaceuticals, bioactive compounds, and other important compounds. This chapter discusses the use of these compounds in drug discovery, drug development, and other relevant applications.

Biographical Memoire for Leslie Hough

Chapter 9: Introduction
Leslie Hough, a renowned carbohydrate chemist, has made significant contributions to the field of carbohydrate chemistry. This chapter provides a biographical memoire for Leslie Hough, highlighting his contributions to the field and his impact on the scientific community.

Chapter 10: Early Life and Education
Leslie Hough was born in 1936 in London, England. He received his Bachelor of Science degree in Chemistry from the University of London in 1958. After completing his undergraduate studies, he pursued his Ph.D. in Organic Chemistry at the University of Cambridge, where he worked under the guidance of Professor Sir Geoffrey Wilkinson.

Chapter 11: Research Career
After completing his Ph.D., Leslie Hough began his research career at the University of Cambridge. He worked as a Research Fellow at the University of Cambridge for several years before moving to the University of California, San Diego (UCSD). At UCSD, he worked as a Professor of Chemistry and held various positions, including the Director of the Carbohydrate Chemistry Institute.

Chapter 12: Contributions to Carbohydrate Chemistry
Leslie Hough's contributions to carbohydrate chemistry are numerous and far-reaching. He has made significant contributions to the synthesis and characterization of various carbohydrates, including sugars, glycosides, and polysaccharides. He has also developed novel methods for the synthesis of complex carbohydrates, such as glycosaminoglycans and polysaccharides.

Chapter 13: Awards and Honors
Leslie Hough has received numerous awards and honors for his contributions to carbohydrate chemistry. He has been awarded the Royal Society of Chemistry's Faraday Medal (2000), the American Chemical Society's Arthur C. Cope Award (2001), and the American Society of Carbohydrate Chemists' Founders Award (2006).

Chapter 14: Conclusion
Leslie Hough's contributions to carbohydrate chemistry have had a profound impact on the field. His work has paved the way for new discoveries and advancements in the synthesis and characterization of carbohydrates. He has also served as a mentor and inspiration to many young scientists, and his legacy will continue to be felt for years to come.

In conclusion, Advances in Carbohydrate Chemistry and Biochemistry,Volume 80, presents a comprehensive overview of the latest developments in this field. The chapters on Vinyl Sulfone-Modified Carbohydrates: Michael Acceptors and 2p Partners for the Synthesis of Functionalized Sugars, Enantiomerically Pure Carbocycles and Heterocycles, and a Biographical Memoire for Leslie Hough offer valuable insights into the synthesis and applications of these important compounds. The book is a valuable resource for researchers, students, and professionals in the field of carbohydrate chemistry and biochemistry.

Weight: 450g
Dimension: 229 x 152 (mm)
ISBN-13: 9780128246283