Advances in Immunology

Advancements in Immunology, Volume 157, is a recent publication that covers current developments and comprehensive reviews in immunology, including topics such as antigen receptor structure and signaling, T cells in brain inflammation, RIG-I/MDA5 activation, GSDMD biology, cGAS-STING pathway, and the CARD8 inflammasome in HIV infection.

Format: Hardback
Length: 108 pages
Publication date: 11 April 2023
Publisher: Elsevier Science Publishing Co Inc

Immunology, a field of study that has been instrumental in understanding and combating various diseases, has seen significant advancements in recent years. One notable publication in this field is Advances in Immunology,Volume 157, which has been a trusted source of information for researchers and practitioners alike. In this latest release, readers can expect to find comprehensive reviews and cutting-edge developments in the field.

The book is divided into several chapters, each covering a different aspect of immunology. Some of the key topics discussed include:

Antigen receptor structure and signaling: This chapter explores the intricate mechanisms by which cells recognize and respond to antigens, which are the substances that trigger an immune response. It discusses the structure and function of antigen receptors, as well as the signaling pathways that are activated upon their interaction with antigens.

T cells in the brain inflammation: T cells play a crucial role in the immune response, and their involvement in brain inflammation has been extensively studied. This chapter discusses the role of T cells in the pathogenesis of diseases such as multiple sclerosis and Alzheimer's disease, as well as the potential therapeutic approaches for these conditions.

The molecular mechanism of RIG-I/MDA5 activation and signaling: RIG-I and MDA5 are sensors that detect viral infections and trigger immune responses. This chapter discusses the molecular mechanisms by which these sensors are activated and the signaling pathways that they activate, which are essential for the development of effective antiviral therapies.

GSDMD biology: GSDMD is a protein that plays a critical role in the regulation of inflammatory responses. This chapter discusses the biology of GSDMD, including its structure, function, and potential therapeutic targets in diseases such as inflammatory bowel disease and cancer.

cGAS-STING pathway: The cGAS-STING pathway is a signaling pathway that detects DNA damage and triggers immune responses. This chapter discusses the role of this pathway in the development of cancer and the potential therapeutic approaches for targeting it.

The CARD8 inflammasome in HIV infection: The CARD8 inflammasome is a protein complex that plays a critical role in the immune response to HIV infection. This chapter discusses the role of the CARD8 inflammasome in the pathogenesis of HIV infection and the potential therapeutic approaches for targeting it.

These are just a few of the chapters that are included in Advances in Immunology,Volume 157. The book provides a comprehensive overview of the latest developments in immunology and is an invaluable resource for researchers, practitioners, and students in the field.

In conclusion, Advances in Immunology,Volume 157, is a must-read for anyone interested in immunology. The book offers a comprehensive and up-to-date overview of the field, covering a wide range of topics and providing valuable insights into the latest research and therapeutic approaches. With its esteemed reputation and expert authorship, this publication is an essential tool for anyone seeking to stay informed and advance their knowledge in this dynamic and rapidly evolving field.

Weight: 312g
Dimension: 159 x 239 x 13 (mm)
ISBN-13: 9780443193286