Advances in Virus Research

Advancements in Virus Research, Volume 113, highlights new advances in the field, including RNA modifications, RNA silencing suppression, animal models, and Enterovirus entry and spread.

Format: Hardback
Length: 118 pages
Publication date: 01 November 2022
Publisher: Elsevier Science & Technology

This ongoing serial, Advances in Virus Research, Volume 113, presents a collection of captivating chapters authored by an esteemed international panel of experts. The volume showcases groundbreaking advancements in the field, offering readers a glimpse into the latest developments. Divided into several sections, the chapters delve into diverse topics such as RNA modifications in viruses and virus-infected cells, the suppression of RNA silencing, the utilization of animal models for alphavirus infection studies, and the intricate mechanisms of enterovirus entry and spread.

The first section explores the intricate mechanisms of RNA modifications in viruses, shedding light on how these modifications impact viral replication, protein expression, and immune evasion. The authors discuss the role of RNA editing enzymes in modifying viral RNAs, as well as the implications of these modifications for virus pathogenesis and vaccine development.

The second section delves into the complex mechanisms of RNA silencing suppression, which plays a crucial role in regulating gene expression in viruses. The authors explore the factors that contribute to RNA silencing, the mechanisms by which viruses evade silencing, and the strategies employed by viruses to overcome silencing defenses. This section provides valuable insights into the host-virus interactions and the potential for developing antiviral therapies.

The third section explores the use of animal models for alphavirus infection studies, which are essential for understanding the pathogenesis and immune response to these viruses. The authors discuss the advantages and limitations of different animal models, as well as the techniques used to study alphavirus infections in vivo. This section highlights the importance of animal models in vaccine development and therapeutics.

The fourth section focuses on the entry and spread of enteroviruses, which are a group of viruses that cause a wide range of diseases, including respiratory infections, meningitis, and encephalitis. The authors discuss the molecular mechanisms of enterovirus entry into cells, the factors that determine viral tropism, and the strategies employed by enteroviruses to evade immune responses. This section provides valuable insights into the control and prevention of enterovirus infections.

In conclusion, Advances in Virus Research, Volume 113, serves as a valuable resource for researchers, students, and healthcare professionals interested in the field of virology. The chapters presented in this volume highlight the latest advancements in RNA modifications, RNA silencing suppression, animal models of alphavirus infection, and enterovirus entry and spread. The comprehensive coverage and expert insights provided by the authors make this volume an essential tool for staying updated with the latest developments in virus research.

Weight: 450g
Dimension: 229 x 152 (mm)
ISBN-13: 9780323989923