Annual Reports on NMR Spectroscopy

Format: Hardback
Length: 142 pages
Publication date: 12 March 2022
Publisher: Elsevier Science & Technology

The 105th volume of Annual Reports on NMR Spectroscopy, a renowned series that has established itself as a premier resource for both specialists and non-specialists interested in new techniques and applications pertaining to NMR spectroscopy, offers a wealth of updated chapters covering diverse topics. These chapters encompass recent advancements in dynamic nuclear polarization-enhanced NMR spectroscopy for organic polymers, as well as the functional and structural characterization of membrane-binding proteins using NMR techniques.

The first chapter, authored by renowned experts, provides a comprehensive overview of dynamic nuclear polarization (DNP)-enhanced NMR spectroscopy, a powerful tool for studying organic polymers. It discusses the principles of DNP, its applications in polymer chemistry, and the recent developments in methodology and instrumentation. The chapter highlights the advantages of DNP over traditional NMR techniques, such as increased sensitivity, selectivity, and resolution, and explores its potential in various fields, including drug discovery, materials science, and biochemistry.

The second chapter focuses on the functional and structural characterization of membrane-binding proteins using NMR techniques. The authors discuss the importance of membrane proteins in various biological processes and the challenges associated with their study. They introduce various NMR methods, such as solid-state NMR, solution NMR, and multi-dimensional NMR, that are used to probe the structure, dynamics, and interactions of membrane-bound proteins. The chapter highlights the key insights gained from these studies in understanding the function of membrane proteins in cellular signaling, drug transport, and disease mechanisms.

The third chapter explores the application of NMR spectroscopy in drug discovery and development. The authors discuss the use of NMR techniques, such as structure determination, dynamics, and interaction studies, to identify potential drug candidates, optimize drug properties, and understand drug-target interactions. They highlight the importance of NMR in drug discovery pipelines, from target identification to preclinical testing, and discuss the challenges and opportunities associated with using NMR in drug discovery.

The fourth chapter focuses on the development of new NMR methodologies and applications. The authors discuss the use of advanced NMR techniques, such as high-field NMR, multidimensional NMR, and solid-state NMR, to study complex biological systems and materials. They highlight the potential of these techniques in areas such as drug discovery, materials science, and biomedicine. The chapter also discusses the challenges and opportunities associated with developing and implementing these new methodologies.

The fifth chapter explores the use of NMR spectroscopy in environmental science and sustainability. The authors discuss the use of NMR techniques to study the structure, dynamics, and interactions of organic pollutants, natural products, and biological materials in the environment. They highlight the potential of NMR in monitoring and managing environmental pollution, developing sustainable waste management strategies, and understanding the impact of environmental factors on human health and ecosystems.

The sixth chapter focuses on the application of NMR spectroscopy in food science and nutrition. The authors discuss the use of NMR techniques to study the structure, dynamics, and interactions of food components, such as proteins, lipids, and carbohydrates. They highlight the potential of NMR in food quality control, food safety assessment, and nutritional analysis. The chapter also discusses the challenges and opportunities associated with using NMR in food science and nutrition.

The seventh chapter explores the use of NMR spectroscopy in biomedicine and clinical research. The authors discuss the use of NMR techniques to study the structure, dynamics, and interactions of biological molecules, such as proteins, nucleic acids, and small molecules. They highlight the potential of NMR in diagnosing and treating diseases, developing new therapeutic agents, and understanding the molecular mechanisms of disease. The chapter also discusses the challenges and opportunities associated with using NMR in biomedicine and clinical research.

The eighth chapter focuses on the application of NMR spectroscopy in materials science and engineering. The authors discuss the use of NMR techniques to study the structure, dynamics, and interactions of materials, such as polymers, metals, and ceramics. They highlight the potential of NMR in developing new materials with improved properties, understanding the structure-property relationships of materials, and developing sustainable materials for energy and environmental applications.

The ninth chapter explores the use of NMR spectroscopy in cultural heritage and archaeology. The authors discuss the use of NMR techniques to study the structure, dynamics, and interactions of ancient artifacts, such as pottery, paintings, and sculptures. They highlight the potential of NMR in dating and authenticating artifacts, understanding the composition and manufacturing techniques of ancient materials, and preserving cultural heritage for future generations.

The tenth chapter focuses on the application of NMR spectroscopy in industrial process monitoring and optimization. The authors discuss the use of NMR techniques to study the structure, dynamics, and interactions of industrial processes, such as chemical reactions, polymerization, and fermentation. They highlight the potential of NMR in optimizing industrial processes, reducing waste and energy consumption, and improving product quality.

The eleventh chapter explores the use of NMR spectroscopy in education and training. The authors discuss the use of NMR techniques to teach students about chemistry, biology, and materials science. They highlight the potential of NMR in enhancing student engagement, improving student understanding of complex concepts, and developing critical thinking skills. The chapter also discusses the challenges and opportunities associated with using NMR in education and training.

The twelfth chapter focuses on the future of NMR spectroscopy. The authors discuss the emerging trends and developments in NMR technology, such as high-field NMR, multidimensional NMR, and solid-state NMR. They highlight the potential of these technologies in expanding the scope of NMR applications, improving the accuracy and precision of NMR measurements, and developing new NMR methodologies and applications. The chapter also discusses the challenges and opportunities associated with the future of NMR spectroscopy.

In conclusion, the 105th volume of Annual Reports on NMR Spectroscopy offers a comprehensive and up-to-date overview of the latest techniques and applications in NMR spectroscopy. The chapters cover a wide range of topics, from dynamic nuclear polarization-enhanced NMR spectroscopy for organic polymers to functional and structural characterization of membrane-binding proteins using NMR. The book is a valuable resource for researchers, scientists, and professionals in various fields, including polymer chemistry, biochemistry, drug discovery, materials science, and environmental science. The authors of the chapters are renowned experts in their respective fields, and their contributions provide valuable insights and knowledge to readers.

The 105th volume of Annual Reports on NMR Spectroscopy, a renowned series that has established itself as a premier resource for both specialists and non-specialists interested in new techniques and applications pertaining to NMR spectroscopy, offers a wealth of updated chapters covering diverse topics.

These chapters encompass recent advancements in dynamic nuclear polarization-enhanced NMR spectroscopy for organic polymers, as well as the functional and structural characterization of membrane-binding proteins using NMR techniques.

The first chapter, authored by renowned experts, provides a comprehensive overview of dynamic nuclear polarization (DNP)-enhanced NMR spectroscopy, a powerful tool for studying organic polymers.

It discusses the principles of DNP, its applications in polymer chemistry, and the recent developments in methodology and instrumentation.

The chapter highlights the advantages of DNP over traditional NMR techniques, such as increased sensitivity, selectivity, and resolution, and explores its potential in various fields, including drug discovery, materials science, and biochemistry.

The second chapter focuses on the functional and structural characterization of membrane-binding proteins using NMR techniques.

The authors discuss the importance of membrane proteins in various biological processes and the challenges associated with their study.

They introduce various NMR methods, such as solid-state NMR, solution NMR, and multi-dimensional NMR, that are used to probe the structure, dynamics, and interactions of membrane-bound proteins.

The chapter highlights the key insights gained from these studies in understanding the function of membrane proteins in cellular signaling, drug transport, and disease mechanisms.

The third chapter explores the application of NMR spectroscopy in drug discovery and development.

The authors discuss the use of NMR techniques, such as structure determination, dynamics, and interaction studies, to identify potential drug candidates, optimize drug properties, and understand drug-target interactions.

They highlight the importance of NMR in drug discovery pipelines, from target identification to preclinical testing, and discuss the challenges and opportunities associated with using NMR in drug discovery.

The fourth chapter focuses on the development of new NMR methodologies and applications.

The authors discuss the use of advanced NMR techniques, such as high-field NMR, multidimensional NMR, and solid-state NMR, to study complex biological systems and materials.

They highlight the potential of these techniques in areas such as drug discovery, materials science, and biomedicine.

The chapter also discusses the challenges and opportunities associated with developing and implementing these new methodologies.

The fifth chapter explores the use of NMR spectroscopy in environmental science and sustainability.

The authors discuss the use of NMR techniques to study the structure, dynamics, and interactions of organic pollutants, natural products, and biological materials in the environment.

They highlight the potential of NMR in monitoring and managing environmental pollution, developing sustainable waste management strategies, and understanding the impact of environmental factors on human health and ecosystems.

The sixth chapter focuses on the application of NMR spectroscopy in food science and nutrition.

The authors discuss the use of NMR techniques to study the structure, dynamics, and interactions of food components, such as proteins, lipids, and carbohydrates.

They highlight the potential of NMR in food quality control, food safety assessment, and nutritional analysis.

The chapter also discusses the challenges and opportunities associated with using NMR in food science and nutrition.

The seventh chapter explores the use of NMR spectroscopy in biomedicine and clinical research.

The authors discuss the use of NMR techniques to study the structure, dynamics, and interactions of biological molecules, such as proteins, nucleic acids, and small molecules.

They highlight the potential of NMR in diagnosing and treating diseases, developing new therapeutic agents, and understanding the molecular mechanisms of disease.

The chapter also discusses the challenges and opportunities associated with using NMR in biomedicine and clinical research.

The eighth chapter focuses on the application of NMR spectroscopy in materials science and engineering.

The authors discuss the use of NMR techniques to study the structure, dynamics, and interactions of materials, such as polymers, metals, and ceramics.

They highlight the potential of NMR in developing new materials with improved properties, understanding the structure-property relationships of materials, and developing sustainable materials for energy and environmental applications.

The ninth chapter explores the use of NMR spectroscopy in cultural heritage and archaeology.

The authors discuss the use of NMR techniques to study the structure, dynamics, and interactions of ancient artifacts, such as pottery, paintings, and sculptures.

They highlight the potential of NMR in dating and authenticating artifacts, understanding the composition and manufacturing techniques of ancient materials, and preserving cultural heritage for future generations.

The tenth chapter focuses on the application of NMR spectroscopy in industrial process monitoring and optimization.

The authors discuss the use of NMR techniques to study the structure, dynamics, and interactions of industrial processes, such as chemical reactions, polymerization, and fermentation.

They highlight the potential of NMR in optimizing industrial processes, reducing waste and energy consumption, and improving product quality.

The eleventh chapter explores the use of NMR spectroscopy in education and training.

The authors discuss the use of NMR techniques to teach students about chemistry, biology, and materials science.

They highlight the potential of NMR in enhancing student engagement, improving student understanding of complex concepts, and developing critical thinking skills.

The chapter also discusses the challenges and opportunities associated with using NMR in education and training.

The twelfth chapter focuses on the future of NMR spectroscopy.

The authors discuss the emerging trends and developments in NMR technology, such as high-field NMR, multidimensional NMR, and solid-state NMR.

They highlight the potential of these technologies in expanding the scope of NMR applications, improving the accuracy and precision of NMR measurements, and developing new NMR methodologies and applications.

The chapter also discusses the challenges and opportunities associated with the future of NMR spectroscopy.

In conclusion, the 105th volume of Annual Reports on NMR Spectroscopy offers a comprehensive and up-to-date overview of the latest techniques and applications in NMR spectroscopy.

The chapters cover a wide range of topics, from dynamic nuclear polarization-enhanced NMR spectroscopy for organic polymers to functional and structural characterization of membrane-binding proteins using NMR.

The book is a valuable resource for researchers, scientists, and professionals in various fields, including polymer chemistry, biochemistry, drug discovery, materials science, and environmental science.

The authors of the chapters are renowned experts in their respective fields, and their contributions provide valuable insights and knowledge to readers.

Weight: 1000g
Dimension: 229 x 152 (mm)
ISBN-13: 9780323988773