Applications of Heterocycles in the Design of Drugs and Agricultural Products

The Applications of Heterocycles in the Design of Drugs and Agricultural Products,Volume 134 in the Advances in Heterocyclic Chemistry series is a comprehensive review of the field, covering topics such as Hydroxy azoles, Cyclic sulfoxides, Thiazoles, fused pyrrolidine heterocycles, 1,4 Disubstituted and 1,4,5 trisubstituted-1,2,3-triazoles, and Conformationally restricted [3.2.2]- and [3.2.1]-3-azabicyclic diamines. It combines descriptive synthetic chemistry and mechanistic insight to understand how chemistry drives the preparation and useful properties of heterocyclic compounds.

Format: Hardback
Length: 330 pages
Publication date: 14 June 2021
Publisher: Elsevier Science Publishing Co Inc

The 134th volume in the Advances in Heterocyclic Chemistry series, titled Applications of Heterocycles in the Design of Drugs and Agricultural Products, is a comprehensive and authoritative resource for organic chemists, polymer chemists, and biological scientists alike. This updated volume encompasses a wide range of topics, including:

Hydroxy azoles as carboxylic acid bioisosteres: This chapter explores the use of hydroxy azoles as potential bioisosteres, which can mimic the properties of carboxylic acids and have applications in drug design.

Cyclic sulfoxides and sulfones in drug design: This chapter discusses the synthesis and pharmacological properties of cyclic sulfoxides and sulfones, which are important intermediates in drug discovery and development.

Thiazoles and topological control in drug design: This chapter explores the use of thiazoles as scaffolds for drug design and their ability to control the conformational properties of molecules, which can have implications for their biological activity.

Applications of fused pyrrolidine [3.3.0] heterocycles in drug design: This chapter discusses the synthesis and pharmacological properties of fused pyrrolidine heterocycles, which are important building blocks in drug discovery.

[1,4] Disubstituted and [1,4,5] trisubstituted-1,2,3-triazoles in drug discovery and development: This chapter explores the synthesis and pharmacological properties of [1,4] disubstituted and [1,4,5] trisubstituted-1,2,3-triazoles, which are important scaffolds for drug discovery.

Conformationally restricted [3.2.2]- and [3.2.1]-3-azabicyclic diamines: This chapter discusses the synthesis and pharmacological properties of conformationally restricted [3.2.2]- and [3.2.1]-3-azabicyclic diamines, which are important scaffolds for drug discovery.

Due to the growing intersection between biology and organic chemistry, the associated nomenclature is being increasingly used in explanations throughout this comprehensive review. Written by established authorities from around the world, this review combines descriptive synthetic chemistry with mechanistic insight to provide a deep understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds.

Overall, Applications of Heterocycles in the Design of Drugs and Agricultural Products, Volume 134 is a valuable resource for researchers and practitioners in the fields of organic chemistry, polymer chemistry, and biological sciences. It offers a comprehensive and up-to-date perspective on the applications of heterocycles in drug and agricultural product design, providing insights into the latest developments and trends in this field.

Weight: 450g
Dimension: 229 x 152 (mm)
ISBN-13: 9780128201817