Aquaporins

This book provides a comprehensive review of our current understanding of aquaporins and their potential applications in various fields. It covers topics such as aquaporin structure, function, and regulation, as well as their role in water transport and other biological processes. The book also discusses the latest research findings and emerging trends in aquaporin research.

Format: Hardback
Length: 365 pages
Publication date: 31 January 2023
Publisher: Springer Verlag, Singapore

Aquaporins (AQPs) are a remarkable class of water-channel proteins that possess the unique ability to selectively permeate water and other small molecules, including glycerol and urea. To date, thirteen distinct water-channel proteins, known as AQP0 to AQP12, have been successfully cloned, shedding light on the intricate mechanisms and physiological functions involved in water transport across biological membranes.

Over the years, the study of water transport across cell membranes has captivated the attention of researchers, and the molecular biology and physiology of aquaporins have played a pivotal role in unraveling these processes. Recent advancements in these fields have provided invaluable insights into how and why water moves across cell membranes. In particular, studies on aquaporin knockout mouse models have revealed that aquaporins are implicated in the development of certain diseases, making them potential targets for the development of selective-inhibitor drugs.

In order to provide a comprehensive and up-to-date account of our current understanding of aquaporins and the future direction of this field, this book offers a state-of-the-art report. By focusing on the significant advancements made over the past 30 years in the biophysics, genetics, protein structure, molecular biology, physiology, pathophysiology, and pharmacology of aquaporins in mammalian cell membranes, the book provides novel insights into further mechanisms and the physiological significance of water and small molecule transport in mammals.

To enhance the value of this resource, fourteen chapters have been updated based on the most recent research articles. Additionally, ten new chapters have been added, covering emerging areas of research and providing a comprehensive overview of the field.

Whether you are a researcher, student, or healthcare professional, this book will serve as a valuable reference for your studies and research endeavors. It will provide you with a comprehensive understanding of aquaporins and their role in water and small molecule transport, and it will inspire you to explore new directions in this exciting field.

Weight: 903g
Dimension: 254 x 178 (mm)
ISBN-13: 9789811974144
Edition number: 2nd ed. 2023