Axon Regeneration: Methods and Protocols

This volume covers various approaches to deciphering cellular and molecular mechanisms of nerve regeneration, leading to functional recovery. It includes in vivo and in vitro models, physical injury models, isolation/analysis of macromolecules, live and fixed imaging of regenerating axons, and quantifying behavioral endpoints. Written in the format of the highly successful Methods in Molecular Biology series, it aims to be a comprehensive guide for researchers.

Format: Hardback
Length: 451 pages
Publication date: 08 March 2023
Publisher: Springer-Verlag New York Inc.

This comprehensive volume delves into diverse strategies employed to unravel cellular and molecular mechanisms underlying successful nerve regeneration, ultimately leading to functional recovery. The chapters present a diverse range of models, encompassing both in vivo and in vitro approaches, physical injury models, techniques for isolating and analyzing various macromolecules, live and fixed imaging of regenerating axons, and methodologies for quantifying behavioral endpoints, enabling the assessment of regenerative success. Written in the format of the highly acclaimed Methods in Molecular Biology series, each chapter begins with an introduction to the topic, outlines the necessary materials and methods, provides helpful tips on troubleshooting and potential pitfalls, and presents step-by-step, readily reproducible protocols. Authored by esteemed experts in the field, Axon Regeneration: Methods and Protocols strives to be an indispensable guide for researchers seeking to advance their understanding of this critical area of neuroscience.

Weight: 1063g
Dimension: 254 x 178 (mm)
ISBN-13: 9781071630112
Edition number: 1st ed. 2023