Biogenic Nanoparticles for Cancer Theranostics

Biogenic Nanoparticles for Cancer Theranostics is a book that discusses the synthesis,cellular interaction,uptake,pharmacokinetics,biodistribution,drug delivery efficiency,and toxicological effects of biogenic nanoparticles for cancer treatment. It is an important reference source for materials scientists and biomedical scientists.

Format: Paperback / softback
Length: 284 pages
Publication date: 21 May 2021
Publisher: Elsevier Science Publishing Co Inc

Biogenic Nanoparticles for Cancer Theranostics delves into the intricate process of synthesizing biogenic nanoparticles to transform them into powerful cancer theranostic agents. This comprehensive book not only outlines the synthesis techniques but also delves into the intricate cellular interactions, uptake mechanisms, pharmacokinetics, biodistribution, drug delivery efficiency, and various biological effects of these nanoparticles. Furthermore, it explores the mechanisms behind their penetration into cancerous tissue, clearance processes, and metabolism. Additionally, the book examines the toxicological effects of biogenic nanoparticles both in vitro and in vivo, providing valuable insights into their safety and potential applications in cancer treatment.

As traditional methods of metal nanoparticle synthesis come with significant drawbacks, such as high energy demands, high costs, and potential environmental concerns, the biosynthesis of metal nanoparticles is gaining increasing prominence. Biosynthesis approaches offer several advantages, including cleanliness, safety, energy efficiency, and environmental friendliness. By harnessing natural processes and biological entities, biosynthesis enables the production of metal nanoparticles with controlled properties and reduced environmental impact.

One of the key advantages of biosynthesis is the ability to tailor the properties of metal nanoparticles to suit specific therapeutic applications. By controlling the size, shape, and surface chemistry of the nanoparticles, researchers can optimize their interactions with cancer cells and enhance their therapeutic efficacy. For instance, gold nanoparticles have been extensively studied for their anticancer properties, particularly their ability to induce apoptosis and inhibit tumor growth. However, the synthesis of gold nanoparticles using conventional methods can be energy-intensive and may produce toxic byproducts. By employing biosynthesis, researchers can develop more sustainable and eco-friendly approaches to gold nanoparticle synthesis, reducing the energy consumption and environmental impact associated with traditional methods.

Another advantage of biosynthesis is the potential for scalability and cost-effectiveness. By using biological entities such as bacteria, fungi, and plants, researchers can produce large quantities of metal nanoparticles at a relatively low cost. This scalability is particularly important for developing affordable and accessible cancer theranostics, as it allows for the widespread distribution and use of these agents in developing countries.

Furthermore, biosynthesis offers the potential for personalized medicine. By incorporating genetic engineering techniques, researchers can modify the properties of metal nanoparticles to target specific cancer cells or tumor types. This personalized approach can improve the efficacy of cancer treatment and reduce the side effects associated with conventional therapies.

In conclusion, Biogenic Nanoparticles for Cancer Theranostics is a valuable resource for materials scientists and biomedical scientists seeking to enhance their understanding of the use of biogenic nanoparticles in cancer treatment. By exploring the synthesis, cellular interactions, pharmacokinetics, biodistribution, drug delivery efficiency, and toxicological effects of these nanoparticles, the book provides a comprehensive overview of the field. The biosynthesis of metal nanoparticles offers a promising approach to overcome the drawbacks of traditional methods, enabling the development of safer, more effective, and sustainable cancer theranostics. As research in this area continues to advance, we can expect to see further breakthroughs in the field, leading to improved outcomes for cancer patients worldwide.

Weight: 590g
Dimension: 235 x 191 (mm)
ISBN-13: 9780128214671