Biomaterials Effect on the Bone Microenvironment - Fabrication, Regeneration, and Clinical Applications

Biomaterials have a significant impact on the bone microenvironment, which plays a crucial role in bone regeneration. This resource provides a comprehensive overview of the structure-activity relationship between biomaterials and microenvironment regulation, covering design strategies, applications, and mechanisms. It also discusses potential challenges and future development directions, as well as the design and initiative principle of tailored biomaterials with various features. The book summarizes and compares numerous biomaterials, evaluating their advantages and features in bone microenvironmental regulation and bone generation. It also explores the stimulation mechanism of the microenvironment to bone generation, including mechanical-support, redox, pro-angiogenesis, inflammatory immune, and anti-aging effects. Additionally, it covers topics such as the role of bone microenvironment and biomaterials in modulation of bone diseases, the relationship between biological factors and physiological functions, and the application of third-generation biomaterials. Biomaterials Effect on the Bone Microenvironment is an ideal resource for materials scientists, biotechnologists, biochemists, bioengineers, orthopedists, and clinical chemists who want to stay up-to-date in this rapidly evolving field.

Format: Hardback
Length: 208 pages
Publication date: 08 February 2023
Publisher: Wiley-VCH Verlag GmbH

Biomaterials have a profound impact on the bone microenvironment, influencing clinical bone regeneration from a diverse range of interdisciplinary researchers. This comprehensive resource delves into the intricate relationship between bone biomaterials and microenvironment regulation, offering a systematic exploration from various perspectives. It encompasses a detailed examination of biomaterials' role in regulating the bone microenvironment, encompassing design strategies, applications, and mechanisms involved. Additionally, the book discusses the methods for manufacturing biomaterials and their clinical translation, highlighting the potential challenges and future development directions in this field.

The book explores the design and initiative principles of tailored biomaterials, emphasizing their bioactive components and physicochemical properties. It provides a comprehensive summary and comparison of numerous biomaterials, including natural and synthetic materials. These materials are evaluated for their advantages and features, particularly in terms of their ability to regulate the bone microenvironment and promote bone generation. Furthermore, the book delves into the intricate stimulation mechanisms of the microenvironment to bone generation, encompassing mechanical-support effects, redox effects, pro-angiogenesis effects, inflammatory immune effects, and anti-aging effects.

In addition to these core topics, the book offers further coverage of sample topics such as the role of the bone microenvironment and its associated biomaterials in modulating bone diseases. It reviews the biomaterials used to regulate the bone microenvironment and explores the relationship between biological factors of various materials and their physiological functions within this environment. The book also discusses the application of the third generation of biomaterials, which aims to regenerate the bone and restore its function.

Overall, Biomaterials Effect on the Bone Microenvironment serves as a valuable resource for clinicians, researchers, and students interested in understanding the impact of biomaterials on bone regeneration and their applications in clinical practice. It provides a comprehensive and up-to-date overview of the field, covering key concepts, research findings, and practical considerations, enabling readers to stay at the forefront of this rapidly evolving area.

Weight: 574g
Dimension: 248 x 175 x 16 (mm)
ISBN-13: 9783527350438