Bioprocessing of Viral Vaccines
Bioprocessing of Viral Vaccines
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This book provides an overview of the manufacturing of viral vaccines using cell culture, covering upstream processing, cell culture, downstream processing, and advanced analytical technologies. It includes case studies of inactivated, attenuated, sub-unit, vectored, and genomic vaccines, aimed at graduate engineers and professionals in the fields of vaccinology, bioprocessing, and biomanufacturing.
Format: Hardback
Length: 320 pages
Publication date: 06 September 2022
Publisher: Taylor & Francis Ltd
This comprehensive book delves into the realm of cell culture-produced viral vaccines, catering to the rapidly expanding research and development needs in academia and industry. It serves as a valuable resource for understanding the fundamental principles of vaccination and the manufacturing processes involved in producing viral vaccines.
The book begins by providing an introduction to the basic concepts of virology and immunology, which form the foundation for comprehending the function and design of viral vaccines. These chapters serve as a primer for readers who may not have a background in these fields.
The heart of the content is dedicated to process development, encompassing upstream processing, cell culture of viral vaccines, downstream processing, and advanced analytical technologies specifically tailored to viral vaccines. These chapters offer in-depth insights into the various stages involved in vaccine manufacturing, ensuring the quality and safety of these vital medical products.
Advanced process analytical technologies (PAT) and Quality by Design (QbD) concepts are introduced within the context of vaccine manufacturing, highlighting their importance in ensuring the robustness and reliability of the production process. Case studies are included to illustrate the application of these concepts, showcasing examples of inactivated, attenuated vaccines, sub-unit vaccines, vectored vaccines, genomic vaccines, and COVID-19 vaccines.
This book is specifically designed for graduate engineers and professionals engaged in the fields of vaccinology, bioprocessing, and biomanufacturing of viral vaccines. It provides a comprehensive and up-to-date understanding of the latest advancements and challenges in this field, equipping readers with the knowledge and skills necessary to contribute to the development and manufacturing of effective viral vaccines.
Weight: 766g
Dimension: 234 x 156 (mm)
ISBN-13: 9781032132112
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