Bisphenol A: A Multi-modal Endocrine Disruptor

BPA is an endocrine-disrupting chemical that has been widely used in consumer products, leading to widespread contamination. Research into BPA has identified multiple modes of action that impact human health and disease development, including epigenetic reprogramming. This book highlights the critical studies in BPA and outlines the connections and disparities in the literature to build a broader understanding of its impact on the environment and human health.

Format: Hardback
Length: 178 pages
Publication date: 12 January 2022
Publisher: Royal Society of Chemistry

Bisphenol A (BPA) is a highly prevalent endocrine-disrupting chemical found in a wide range of consumer products. Its extensive use has resulted in widespread contamination of the air, soil, and water, leading to widespread human exposure. Over the past decade, research into BPA has surged, revealing numerous modes of action that have significant implications for human health and disease development. While BPA has been known for its estrogenic effects, emerging literature has uncovered several non-receptor-mediated mechanisms, such as epigenetic reprogramming, that can have long-term impacts on population health.

This book serves as a valuable resource for postgraduates and researchers across various disciplines, including toxicology, epigenetics, and cancer epidemiology. It highlights the diverse ways in which BPA can reprogram cells genetically and metabolically. By compiling critical studies on BPA and outlining the connections and disparities in the literature, the book aims to provide a comprehensive understanding of this complex endocrine-disrupting chemical and its profound effects on the environment and human health.

The prevalence of BPA in consumer products is a concern, as it can leach into food and beverages and be ingested by humans. Studies have shown that BPA can affect various aspects of human health, including reproductive development, metabolism, and immune function. It has been linked to an increased risk of obesity, diabetes, and certain types of cancer. Additionally, BPA has been shown to interfere with the normal functioning of hormones, which can have cascading effects throughout the body.

Given the potential risks associated with BPA, there has been a growing movement to reduce its use in consumer products. Many countries have implemented regulations or bans on the production and use of BPA, and manufacturers have begun to explore alternative materials that are less harmful to human health. However, it is important to note that BPA is still widely present in many products, and it can be difficult to avoid exposure completely.

To mitigate the risks associated with BPA exposure, individuals can take several steps. For example, they can choose to drink water from stainless steel or glass bottles rather than plastic bottles, which are often made with BPA. They can also opt for products that are labeled as BPA-free or made with alternative materials. Additionally, eating a healthy diet rich in fruits, vegetables, and whole grains can help support a healthy immune system and reduce the risk of chronic diseases.

In conclusion, Bisphenol A (BPA) is a highly prevalent endocrine-disrupting chemical that has significant implications for human health and disease development. Its extensive use has led to widespread contamination of the air, soil, and water, resulting in widespread human exposure. While research into BPA has grown exponentially over the past decade, there is still much to be learned about its modes of action and its long-term impacts on population health. By compiling critical studies on BPA and outlining the connections and disparities in the literature, this book serves as a valuable resource for postgraduates and researchers across various disciplines. It highlights the diverse ways in which BPA can reprogram cells genetically and metabolically and emphasizes the importance of reducing its use in consumer products to mitigate the risks associated with exposure.

Weight: 454g
Dimension: 234 x 156 (mm)
ISBN-13: 9781839162060