Cancer Immunology and Immunotherapy: Volume 1 of Delivery Strategies and Engineering Technologies in Cancer Immunotherapy

Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy explores the challenges of delivering immuno-oncology therapies and the potential of nanotechnology-based targeted delivery strategies and locally-administered immunogenic scaffolds to improve clinical success.

Format: Paperback / softback
Length: 548 pages
Publication date: 27 August 2021
Publisher: Elsevier Science Publishing Co Inc

Immuno-oncology (IO) is a rapidly evolving field at the intersection of immunology and cancer biology, paving the way for innovative therapeutic approaches like chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies. These clinically approved treatments have shown tremendous promise in treating certain types of cancer, highlighting the potential for further advancements in cancer therapy. While currently approved IO strategies have demonstrated remarkable success in select cancer cases, their broader application could significantly improve clinical outcomes, particularly for diseases like pancreatic cancer and brain tumors where IO has faced challenges.

Nanotechnology-based targeted delivery strategies hold immense potential to enhance the delivery efficiency of IO agents and open up new avenues for novel therapeutic and vaccination strategies. By utilizing nanotechnology, scientists can design materials with specific properties that target cancer cells while minimizing side effects on healthy tissues. This approach can improve the efficacy of IO therapies and increase their accessibility to patients.

In addition to targeted delivery, locally administered immunogenic scaffolds and therapeutic strategies, such as the use of STING agonists, can benefit from rationally designed biomaterials and delivery approaches. These strategies aim to stimulate the immune system and enhance the body's ability to fight cancer. Rationally designed biomaterials can improve the stability, biocompatibility, and efficacy of these agents, ensuring optimal delivery and response.

Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy serves as a comprehensive resource that brings together the scientific and medical communities involved in immunology, cancer biology, and therapeutics. It explores potential solutions from the nanotechnology and drug delivery perspectives, providing a comprehensive treaty that addresses the challenges faced in delivering immuno-oncology therapies. By fostering collaboration and knowledge exchange, this book aims to accelerate the development of effective and sustainable IO treatments for cancer patients worldwide.

Weight: 1130g
Dimension: 235 x 191 (mm)
ISBN-13: 9780128233979