Cancer Immunotherapy Principles and Practice

The second edition of Cancer Immunotherapy Principles and Practice, from the Society for Immunotherapy of Cancer (SITC), is the definitive resource for information on tumor immunology and cancer immunotherapy treatments. It covers major topics and innovations, including cancer genomics, immunogenic cell death, cancer and stromal cell-intrinsic pathways of immune resistance, cancer immune exclusion, adoptive cell therapy, metabolomics, tumor mutation burden, immunotherapy in combination with radiation therapy, synthetic biology, and more. It is essential for scientists and clinicians looking to expand their knowledge base of this dynamic field.

Format: Hardback
Length: 1000 pages
Publication date: 01 September 2021
Publisher: Springer Publishing Co Inc

This second edition of Cancer Immunotherapy Principles and Practice, from the Society for Immunotherapy of Cancer (SITC), remains the definitive resource for information on tumor immunology and cancer immunotherapy treatments. An essential reference for both novice and experienced cancer researchers, oncologists, and related practitioners alike, the book not only guides readers through the fundamental scientific principles of the field all the way to translational and practical clinical applications for treating and managing oncologic disease, but also provides a comprehensive understanding of the regulatory processes that support the safe and effective delivery of immunotherapy to patients with cancer. The expanded and updated second edition now spans 68 chapters, including 12 new chapters, covering major topics and innovations that have shaped the rapid development of immunotherapy and its ascension into the standard of care as first-line treatment for a growing number of disease settings. New to this edition are chapters with deeper insight into our understanding of cancer genomics and determinants of response, immunogenic cell death, cancer and stromal cell-intrinsic pathways of immune resistance, cancer immune exclusion, adoptive cell therapy, metabolomics, tumor mutation burden, immunotherapy in combination with radiation therapy, synthetic biology, and more. Complete with detailed illustrations, tables, and key points for targeted reference, Cancer Immunotherapy Principles and Practice, Second Edition is the most comprehensive and authoritative resource for scientists and clinicians looking to expand their knowledge base of this dynamic field.

Key Features:

Offers key insights and perspectives on cancer immunotherapy, including its historical development, basic principles, and clinical applications.

Explores the role of the immune system in cancer development and progression, as well as the mechanisms of immune resistance and immune checkpoint therapy.

Covers a wide range of immunotherapy modalities, such as monoclonal antibodies, checkpoint inhibitors, adoptive cell therapy, and cancer vaccines.

Provides detailed descriptions of cancer immunotherapy trials and clinical studies, including results, mechanisms of action, and potential side effects.

Highlights the importance of patient selection, biomarker analysis, and personalized treatment approaches in cancer immunotherapy.

Discusses the role of the tumor microenvironment in immune suppression and immune activation, and the strategies used to manipulate it for therapeutic benefit.

Includes chapters on emerging technologies and techniques in cancer immunotherapy, such as gene editing, synthetic biology, and immunomodulators.

Written by a team of internationally renowned experts in the field, Cancer Immunotherapy Principles and Practice, Second Edition is an invaluable resource for scientists, clinicians, and researchers seeking to advance their understanding and practice of cancer immunotherapy.

Weight: 2294g
Dimension: 225 x 288 x 41 (mm)
ISBN-13: 9780826137425
Edition number: 2 Revised edition