Chiral Phosphorous Based Ligands in Earth-Abundant Transition Metal Catalysis

Chiral Phosphorous Based Ligands in Earth-Abundant Transition Metal Catalysis is a comprehensive book that covers the progress in chiral phosphine ligand chemistry and their application in enantioselective transformations. It is essential for organic chemistry researchers working in asymmetric catalysis, synthetic methodologies, and total synthesis.

Format: Paperback / softback
Length: 320 pages
Publication date: 01 May 2023
Publisher: Elsevier - Health Sciences Division

Chiral Phosphorous Based Ligands in Earth-Abundant Transition Metal Catalysis is a comprehensive and up-to-date review of the field of chiral phosphine ligand chemistry, encompassing significant advancements in enantioselective transformations catalyzed by earth-abundant transition metals. This book offers a profound and authoritative understanding of key topics related to asymmetric catalysis based on earth-abundant transition metals and chiral phosphine ligands, making it an invaluable resource for organic chemistry researchers engaged in asymmetric catalysis, synthetic methodologies, and total synthesis.

The development of novel chiral phosphine ligands is a crucial area of research in organic synthesis, materials science, and medicinal chemistry. These ligands play a pivotal role in achieving precise stereo control in numerous earth-abundant transition metal-catalyzed reactions, offering one of the most effective approaches to producing valuable optically active chemicals.

The book begins by providing an overview of the historical background and fundamental principles of chiral phosphine ligand chemistry. It then delves into the latest developments in the synthesis, characterization, and application of chiral phosphine ligands in various asymmetric transformations, including Heck, Suzuki, Michael, and Rhodenization reactions. Special attention is given to the use of chiral phosphine ligands in the asymmetric synthesis of complex organic molecules, such as pharmaceuticals, natural products, and agrochemicals.

In addition to covering the synthesis and application of chiral phosphine ligands, the book discusses the development of new chiral phosphine ligand architectures and their impact on catalysis. It explores the use of chiral phosphine ligands in combination with other catalysts, such as organocatalysts and transition metal complexes, to enhance selectivity and efficiency in asymmetric reactions. The book also discusses the challenges and opportunities associated with the use of chiral phosphine ligands in industrial applications, including drug discovery and materials synthesis.

Chiral Phosphorous Based Ligands in Earth-Abundant Transition Metal Catalysis is written in a clear and accessible style, making it suitable for both advanced students and researchers in the field. The book includes numerous examples, figures, and tables to illustrate key concepts and facilitate understanding. It also provides references to relevant literature and research papers for further exploration.

In conclusion, Chiral Phosphorous Based Ligands in Earth-Abundant Transition Metal Catalysis is a valuable resource for organic chemistry researchers and practitioners interested in asymmetric catalysis, synthetic methodologies, and total synthesis. The book provides a comprehensive and up-to-date overview of the field, covering key topics such as ligand synthesis, catalysis, and application. It is an essential read for anyone seeking to advance their knowledge and expertise in this rapidly evolving area of research.

Dimension: 152 x 229 (mm)
ISBN-13: 9780323852258