Chromatin: Structure, Function, and History

Chromatin: Structure, Function, and History provides an overview of chromatin biology, covering nucleosome recognition, folding, positioning, histone variants, modifications, and remodeling. It highlights key insights and recent developments, such as genome-wide approaches and imaging innovations, and aims to instill an appreciation for chromatin's role in modern research.

Format: Paperback / softback
Length: 584 pages
Publication date: 20 June 2024
Publisher: Elsevier Science Publishing Co Inc

Chromatin: Structure, Function, and History delves into the fundamental aspects of chromatin biology, commencing with the groundbreaking discoveries that ultimately led to the recognition of the nucleosome as the fundamental building block of chromatin. The chapter explores chromatin folding, nucleosome positioning, and the diverse histone variants, shedding light on their roles in shaping chromatin structure. Additionally, it delves into the realm of chromatin modifications and remodeling, a field that experienced a significant surge of interest in the early to mid-1990s, propelling epigenetics into the spotlight.

The book pays close attention to the methods and experimental approaches employed that have yielded crucial insights and recent advancements. It highlights the use of genome-wide approaches and innovative imaging techniques, emphasizing their significance in unraveling the intricate dynamics of chromatin. By presenting a comprehensive historical background alongside detailed discussions of contemporary studies, the book endeavors to instill in the reader a profound appreciation for both our current understanding of chromatin structure and function and the remarkable journey that has positioned chromatin at the forefront of modern research.

Weight: 1174g
Dimension: 192 x 231 x 31 (mm)
ISBN-13: 9780128148099