Clinical Decision Support for Pharmacogenomic Precision Medicine: Foundations and Implementation

Clinical Decision Support for Pharmacogenomic Precision Medicine: Foundations and Implementation provides an overview of methods and strategies for translating genomic medicine to clinical practice, including incorporating pharmacogenetics into electronic health records, CDS methods and infrastructure, economic evaluation, hospital administration roles, and patient counseling aspects.

Format: Paperback / softback
Length: 296 pages
Publication date: 01 June 2022
Publisher: Elsevier Science Publishing Co Inc

Clinical Decision Support for Pharmacogenomic Precision Medicine: Foundations and Implementation is a comprehensive guide that provides insights, methodologies, and strategies for effectively translating genomic medicine into clinical practice. Written by esteemed authors, the book delves into various aspects of incorporating pharmacogenetics into electronic health records (EHRs), clinical decision support (CDS) methods and infrastructure, economic evaluation, the role of hospital administrations in integration, and patient counseling considerations. By empowering clinicians, researchers, translational scientists, and data and IT experts, this book serves as a valuable resource for navigating the intricate landscape of CDS for pharmacogenomic precision medicine.

The book offers overviews of key topics, including:

* Incorporating Pharmacogenetics into Electronic Health Records: The authors discuss the challenges and opportunities of integrating pharmacogenetic information into EHRs, highlighting the importance of standardized data formats and effective data exchange mechanisms.
* Clinical Decision Support Methods and Infrastructure: The book explores various CDS methods, such as rule-based systems, decision trees, and artificial intelligence algorithms, and discusses their strengths, limitations, and potential applications in pharmacogenomic precision medicine. It also covers CDS infrastructure, including data warehouses, clinical information systems, and informatics platforms, and discusses their role in facilitating effective CDS implementation.
* Economic Evaluation of Pharmacogenomic Precision Medicine: The authors examine the economic implications of implementing pharmacogenomic precision medicine, including cost-benefit analysis, cost-effectiveness analysis, and pharmacoeconomic modeling. They discuss the challenges and opportunities of assessing the value of genetic testing and personalized medicine interventions from a healthcare system perspective.
* Hospital Administrations' Role and Needs in Integration: The book explores the role of hospital administrations in integrating pharmacogenomic precision medicine into clinical practice. It discusses the challenges and opportunities of establishing effective governance structures, developing policies and procedures, and ensuring seamless integration of genetic testing and personalized medicine into healthcare delivery.
* Patient Counseling Aspects: The authors emphasize the importance of patient counseling in the context of pharmacogenomic precision medicine. They discuss the challenges and opportunities of providing patients with accurate and comprehensive information about their genetic testing results, the potential benefits and risks of personalized medicine interventions, and the importance of patient engagement and shared decision-making.

Illustrative case studies of existing gene networks, including CSER, eMERGE, the IGNITE network, DIGITIZE, the CDS Learning Network (RTI), ClinGen, Ubiquitous, and CDS Hooks, are provided throughout the book to illustrate real-world applications of pharmacogenomic precision medicine. These case studies showcase the successful integration of genetic testing and personalized medicine into clinical practice, highlighting the potential benefits and challenges encountered along the way.

In conclusion, Clinical Decision Support for Pharmacogenomic Precision Medicine: Foundations and Implementation is a valuable resource for healthcare professionals, researchers, and policymakers interested in advancing the field of pharmacogenomic precision medicine. By providing comprehensive overviews, methodologies, and strategies, the book empowers individuals to effectively navigate the complex landscape of CDS and implement personalized medicine approaches that improve patient outcomes and healthcare efficiency.

Weight: 450g
Dimension: 235 x 191 (mm)
ISBN-13: 9780128244531