Cognition in Parkinson's Disease

Cognition in Parkinson's Disease, Volume 269 in the Progress in Brain Research series, highlights new advances in the field, with interesting chapters on timely topics such as cognition in prodromal Parkinson's disease, epidemiology, real-life consequences, animal models, functional neuroanatomy, neuroimaging, cognitive dysfunction, neuropsychiatric aspects, and neuropsychology.

Format: Hardback
Length: 478 pages
Publication date: 18 February 2022
Publisher: Elsevier - Health Sciences Division

Cognition in Parkinson's Disease, Volume 269 in the Progress in Brain Research series, presents a comprehensive exploration of the latest advancements in this field. This new volume offers captivating chapters on diverse and timely topics, such as Cognition in Prodromal Parkinson's Disease, The Epidemiology of Cognitive Function in Parkinson's Disease, Real-Life Consequences of Cognitive Dysfunction in Parkinson's Disease, Animal Models of Cognition in Parkinson's Disease, Functional Neuroanatomy of Cognition in Parkinson's Disease, Neuroimaging Approaches to Cognition in Parkinson's Disease, Cognitive Dysfunction and Neuropsychiatric Aspects of Parkinson's Disease, Neuropsychology of Parkinson's Disease, Cholinergic Systems, Attentional-Motor Integration, and Cognitive Control in Parkinson Disease, among many others.

Parkinson's disease is a progressive neurological disorder that affects movement, coordination, and balance. It is characterized by the degeneration of dopamine-producing neurons in the brain, leading to a decrease in dopamine levels. This reduction in dopamine can cause a range of symptoms, including tremors, stiffness, slow movement, and difficulty with cognitive functions such as memory, attention, and decision-making.

Cognition in Parkinson's disease refers to the ability to think, remember, and make decisions. Cognitive dysfunction is a common feature of Parkinson's disease, and it can have significant impacts on the quality of life of individuals with the condition. Cognitive impairment can occur in different stages of Parkinson's disease, and it can vary depending on the individual's symptoms and overall health.

The epidemiology of cognitive function in Parkinson's disease is an important area of research. Studies have shown that cognitive decline is a common feature of Parkinson's disease, and it is associated with various factors, including age, disease duration, and severity of symptoms. Cognitive decline can also be influenced by other factors, such as depression, anxiety, and sleep disturbances.

Real-life consequences of cognitive dysfunction in Parkinson's disease can be significant. Individuals with cognitive impairment may have difficulty with daily activities such as cooking, driving, and managing finances. They may also experience social isolation and reduced quality of life. Cognitive dysfunction can also lead to falls and other accidents, as individuals may have difficulty with balance and coordination.

Animal models of cognition in Parkinson's disease have been used to study the mechanisms underlying cognitive impairment in the condition. These models allow researchers to study the effects of dopamine depletion on cognitive functions and to test potential treatments. Animal models have shown that cognitive impairment in Parkinson's disease can be reversed by treatments such as dopamine replacement therapy and cognitive training.

Functional neuroanatomy of cognition in Parkinson's disease is an important area of research. Studies have shown that cognitive impairment in Parkinson's disease is associated with changes in the brain's reward and motivation systems. Researchers are studying the effects of dopamine depletion on these systems and exploring potential treatments that target these areas.

Neuroimaging approaches to cognition in Parkinson's disease have been used to study the effects of dopamine depletion on brain structure and function. These approaches include magnetic resonance imaging (MRI), positron emission tomography (PET), and functional magnetic resonance imaging (fMRI). Neuroimaging studies have shown that cognitive impairment in Parkinson's disease is associated with changes in brain regions such as the prefrontal cortex, striatum, and hippocampus.

Cognitive dysfunction and neuropsychiatric aspects of Parkinson's disease are closely linked. Cognitive impairment can lead to depression, anxiety, and other mood disorders in individuals with Parkinson's disease. It can also increase the risk of developing dementia, such as Alzheimer's disease.

Neuropsychology of Parkinson's disease is an important area of research that focuses on understanding the cognitive and behavioral effects of Parkinson's disease. Neuropsychologists use a variety of techniques, such as cognitive testing, neuropsychological assessment, and behavioral therapy, to help individuals with Parkinson's disease manage their symptoms and improve their quality of life.

Cholinergic systems are important in the brain's cognitive functions. Studies have shown that cognitive impairment in Parkinson's disease is associated with changes in the brain's cholinergic system. Researchers are studying the effects of cholinergic drugs on cognitive function in Parkinson's disease and exploring potential treatments that target this system.

Attentional-motor integration is a critical component of cognitive function. Studies have shown that cognitive impairment in Parkinson's disease is associated with changes in attentional-motor integration. Researchers are studying the effects of cognitive training and other interventions on attentional-motor integration in Parkinson's disease and exploring potential treatments that target this area.

Cognitive control is a critical component of cognitive function. Studies have shown that cognitive impairment in Parkinson's disease is associated with changes in cognitive control. Researchers are studying the effects of cognitive training and other interventions on cognitive control in Parkinson's disease and exploring potential treatments that target this area.

In conclusion, cognition in Parkinson's disease is a complex and multifaceted area of research. The latest advances in this field have shed light on the mechanisms underlying cognitive impairment in Parkinson's disease and have led to the development of new treatments and interventions. Continued research in this area is essential to improve the quality of life of individuals with Parkinson's disease and to better understand the underlying mechanisms of cognitive impairment in the condition.

Weight: 1144g
Dimension: 200 x 245 x 30 (mm)
ISBN-13: 9780323901642