Comparative Mammalian Immunology: The Evolution and Diversity of the Immune Systems of Mammals

A comprehensive review of the current knowledge of mammalian immune systems, including recent research on marine mammals, bats, marsupials, and lesser-known species, with chapters on primates and rodents. It utilizes genomic sequences to identify common and unique features of each mammal's immune system, highlighting the complex, coordinated, and controlled interactions that have evolved to protect the host against disease.

Format: Paperback / softback
Length: 458 pages
Publication date: 24 February 2023
Publisher: Elsevier Science & Technology

Comparative Mammalian Immunology: The Evolution and Diversity of the Immune Systems of Mammals is a comprehensive review of the current knowledge of mammalian immune systems, taking a comparative approach. This reference covers recent research on the immune systems of marine mammals, bats, and marsupials, as well as lesser-known species. Chapters on primates and rodents, respectively, include the immune systems of humans and laboratory mice. Additionally, the book utilizes the latest genomic sequences of mammals to identify both common and unique features of each mammal's immune system.

The book delves into the intricate and coordinated series of interactions between cells and molecules that have evolved to protect the host against disease. Mammals, as a highly diverse group of animals, have undergone various selective pressures that have shaped their immune systems. These pressures result in distinct differences in the organization and function of their immune systems, particularly in gene families characterized by complexity and polymorphism.

The immune systems of mammals exhibit a remarkable level of complexity and adaptability. They are capable of recognizing and responding to a wide range of pathogens, including viruses, bacteria, and parasites. These immune responses are orchestrated by a network of cells and molecules that work together in a coordinated manner.

One of the key features of mammalian immune systems is their ability to adapt to changing environments. This adaptability is facilitated by the presence of genetic diversity within mammalian populations. Genetic variations allow for the development of immune responses that are specific to particular pathogens or environmental challenges.

Another important aspect of mammalian immune systems is their ability to mount immune responses that are tailored to the specific needs of the host. This is achieved through the activation of different immune cell types and the production of specific cytokines and antibodies.

The immune systems of mammals also play a crucial role in the development and progression of cancer. Research has shown that certain immune cells and pathways can contribute to the development and progression of cancer, while others can suppress tumor growth. Understanding the role of the immune system in cancer is important for developing new treatments and therapies.

In conclusion, Comparative Mammalian Immunology: The Evolution and Diversity of the Immune Systems of Mammals provides a comprehensive overview of the current knowledge of mammalian immune systems. The book explores the evolution and diversity of immune systems across different mammalian species, highlighting the complex interactions between cells and molecules that protect the host against disease. By examining the immune systems of humans, laboratory mice, and other mammals, the book sheds light on the unique features and adaptations of each species and contributes to our understanding of the immune system as a whole.

Weight: 1224g
Dimension: 212 x 274 x 29 (mm)
ISBN-13: 9780323952194