Competitive Strategies in Life Sciences

Protein engineering and host cell culture techniques are used to develop and manufacture biologics and other bio-molecules for a hurdle-free life with good health. The first volume of this series discusses the latest information on how the classical stepwise host cells culture methodology has been changed to fully continuous or partially continuous host cells culture process to economize the biopharmaceutical products manufacturing process. It also narrates a brief history on the conceptual development of new thoughts in designing biotechnology industries for commercial production of therapeutic proteins with structural modification. The most interesting part of the volume is newly developed concept on bioprinting, which explains how to design and fabricate animate objects by fusing or depositing material of interest in the form of powders, solid dusts, metal, liquid or even living cells or tissues by layers to produce 3D objectives. The first volume ends with the latest information on the current trend in the biologics market, market dynamic, drives, and opportunities with challenges.

Format: Paperback / softback
Length: 189 pages
Publication date: 23 October 2021
Publisher: Springer Verlag, Singapore

Tailoring biomolecules through protein engineering and host cell culture techniques represents a remarkable achievement in modern applied life sciences. These advanced methods apply the fundamental principles of biotechnology to develop and manufacture biologics and other related bio-molecules, aimed at enhancing our quality of life and promoting good health.

In the current market, a significant portion of biologics is derived from genetically modified host cells. These bio-formulations, including antibodies, nucleic acid products, and vaccines, are meticulously crafted through two main steps: upstream processing and downstream processing.

The first volume of this series delves into the latest advancements in transforming the traditional stepwise host cell culture methodology into fully continuous or partially continuous processes. This transformation is driven by the goal of optimizing the manufacturing of biopharmaceutical products. Additionally, the volume provides a concise historical overview of the conceptual development of new ideas in designing biotechnology industries for the commercial production of diverse therapeutic proteins with structural modifications based on clinical requirements.

The readers will be captivated by the latest discoveries and developments in applied life sciences, which facilitate the design of innovative biomolecules for healthcare. The most intriguing aspect of this volume is the newly developed concept of bioprinting. It elucidates the process of creating animate objects by fusing or depositing material of interest in various forms, such as powders, solid dusts, metals, liquids, or even living cells or tissues, through layers. This technique enables the production of 3D objectives, offering exciting possibilities in fields such as medicine, tissue engineering, and biofabrication.

The first volume concludes with the latest information on the current trends in bioprinting technology. It highlights the advancements in materials, printing methods, and applications, which are driving the field forward. By leveraging bioprinting, researchers and scientists can fabricate complex structures and organs with precision and efficiency, paving the way for personalized medicine, regenerative therapies, and drug discovery.

In summary, the first volume of this series provides a comprehensive and insightful exploration into the world of biomolecule tailoring and host cell culture techniques. It highlights the significant contributions of biotechnology to healthcare and showcases the promising applications of bioprinting in various fields. The knowledge and insights gained from this volume will undoubtedly inspire researchers, scientists, and healthcare professionals to push the boundaries of innovation and improve human well-being.

Weight: 326g
Dimension: 235 x 155 (mm)
ISBN-13: 9789811575921
Edition number: 1st ed. 2020