Conceptual Development of Industrial Biotechnology for Commercial Production of Vaccines and Biopharmaceuticals

Industrial biotechnology is used to produce biopharmaceuticals and vaccines sustainably, with a focus on the value chain transfer process. This is a useful reference for students, researchers, and scientists in biotechnology, pharmaceutical science, medical sciences, and the R&D division of biotechnology-based industries. The global market for vaccines, especially COVID-19, is tremendous, and recombinant DNA technology and protein engineering are key to producing quality bio-products.

Format: Paperback / softback
Length: 310 pages
Publication date: 20 March 2023
Publisher: Elsevier Science Publishing Co Inc

The book titled "Conceptual Development of Industrial Biotechnology for Commercial Production of Biopharmaceuticals and Vaccines" offers valuable insights into integrating sustainability into the biologic drug production process. It provides a comprehensive compilation of facts and figures that are instrumental in monitoring the value chain transfer of super-quality biologics, aiming to enhance profitability for promoters. Furthermore, this book serves as a valuable reference for students, researchers, and scientists engaged in biotechnology, pharmaceutical science, medical sciences, and the R&D divisions of biotechnology-based industries.

The field of biotechnology has witnessed a remarkable transformation through the integration of medical sciences, physical science, and engineering. This convergence has paved the way for innovative approaches and the development of timely sources. The current global market for vaccines, particularly in response to the COVID-19 pandemic, is immense. Bivalent oral polio vaccines, diphtheria, tetanus-containing, and measles-containing vaccines have a high demand internationally, and recombinant DNA technology and protein engineering play crucial roles in producing high-quality bio-products.

The book delves into the conceptual development of industrial biotechnology, emphasizing the importance of sustainable practices in biologic drug production. It explores various topics such as process development, fermentation technology, downstream processing, and quality control. By leveraging cutting-edge technologies and innovative approaches, the book aims to address the challenges faced by the biopharmaceutical and vaccine industries.

One of the key aspects discussed in the book is the integration of medical sciences and engineering to enhance the production of biopharmaceuticals and vaccines. The authors highlight the importance of understanding the biological mechanisms and pathways involved in drug development, as well as the application of advanced technologies to improve the efficiency and effectiveness of manufacturing processes.

Furthermore, the book emphasizes the role of fermentation technology in the production of biopharmaceuticals and vaccines. It explores different fermentation platforms, such as batch, fed-batch, and continuous fermentation, and discusses the optimization of fermentation conditions to enhance product yield and quality. The authors also discuss the use of genetic engineering techniques, such as recombinant DNA technology and protein engineering, to modify the properties of microorganisms and improve their productivity in the production of biopharmaceuticals and vaccines.

Downstream processing is another critical aspect of biologic drug production that is extensively covered in the book. It includes topics such as purification, formulation, and stability testing, which are essential for ensuring the safety and efficacy of biopharmaceuticals and vaccines. The authors discuss the latest advancements in purification technologies, such as high-performance liquid chromatography (HPLC) and ultrafiltration, as well as the development of novel formulation strategies to improve the stability and bioavailability of biologics.

Quality control is another crucial aspect of biologic drug production that is emphasized in the book. It includes the development and implementation of robust quality management systems, as well as the use of analytical techniques such as chromatography, immunoassay, and microbiology to monitor the quality of biopharmaceuticals and vaccines throughout the production process. The authors also discuss the importance of regulatory compliance and the need for robust quality control measures to ensure the safety and efficacy of biopharmaceuticals and vaccines.

In conclusion, the book titled "Conceptual Development of Industrial Biotechnology for Commercial Production of Biopharmaceuticals and Vaccines" offers valuable insights into integrating sustainability into the biologic drug production process. It provides a comprehensive compilation of facts and figures that are instrumental in monitoring the value chain transfer of super-quality biologics, aiming to enhance profitability for promoters. Furthermore, this book serves as a valuable reference for students, researchers, and scientists engaged in biotechnology, pharmaceutical science, medical sciences, and the R&D divisions of biotechnology-based industries. The integration of medical sciences, physical science, and engineering has opened up new avenues for innovation and progress in the biopharmaceutical and vaccine industries, and this book serves as a timely source of information and guidance for those seeking to contribute to this field.

Weight: 450g
Dimension: 235 x 191 (mm)
ISBN-13: 9780443187483