Contemporary Approaches to the Study of Pain: From Molecules to Neural Networks

This volume explores experimental approaches that are revolutionizing our understanding of the neurobiology of pain, including gene expression profiling, electrophysiological investigation, calcium imaging, and somatosensory behaviors. It provides detailed advice from specialists to obtain successful results in the laboratory.

Format: Hardback
Length: 458 pages
Publication date: 27 May 2022
Publisher: Springer-Verlag New York Inc.

This groundbreaking volume explores experimental approaches that are currently revolutionizing our understanding of the neurobiology of pain. The chapters delve into a wide range of cutting-edge methods, encompassing the identification of gene expression profiles, transcriptomes, or translatomes, from individual cells or defined groups of cells in rodents and primates. These methods include the electrophysiological investigation of human tissues, such as human dorsal root ganglion neurons, as well as the assessment of modality response profiles of neurons using calcium imaging in vitro and in vivo. Additionally, the book explores somatosensory behaviors in rodents using high-speed videography and machine learning.

In the renowned Neuromethods series style, the chapters provide detailed guidance from experts to ensure successful outcomes in your laboratory. This comprehensive and timely book is a valuable resource for scientists and researchers seeking to advance their knowledge and contribute to the field of pain research. By employing these innovative techniques, researchers can gain a deeper insights into the mechanisms underlying pain perception and develop new therapeutic strategies to alleviate pain and improve patient outcomes.

Weight: 1078g
Dimension: 254 x 178 (mm)
ISBN-13: 9781071620380
Edition number: 1st ed. 2022