Contemporary Management of Metastatic Colorectal Cancer: A Precision Medicine Approach

Contemporary Management of Metastatic Colorectal Cancer: A Precision Medicine Approach is a comprehensive book that provides evidence-based practice recommendations for treating patients with metastatic colorectal cancer. It covers topics such as pre-operating imaging, molecular markers, neoadjuvant therapy, synchronous colorectal liver metastasis, minimally invasive approaches, immunotherapy, targeted therapies, and survivorship, making it a valuable resource for practitioners, cancer researchers, oncologists, graduate students, and members of biomedical research.

Format: Paperback / softback
Length: 326 pages
Publication date: 27 June 2022
Publisher: Elsevier Science & Technology

Here is the rephrased text:

Contemporary Management of Metastatic Colorectal Cancer: A Precision Medicine Approach is a comprehensive guide that summarizes the current knowledge and provides evidence-based practice recommendations for treating patients with metastatic colorectal cancer. The book delves into various topics, including pre-operative imaging, the utilization of molecular markers in treatment decision-making, neoadjuvant therapy, synchronous colorectal liver metastasis, and minimally invasive approaches. Additionally, it explores immunotherapy, targeted therapies, and survivorship, making it an invaluable resource for practitioners, cancer researchers, oncologists, graduate students, and members of the biomedical research community who seek to gain deeper insights into novel treatments for colorectal cancer metastasis.

Pre-operative imaging plays a crucial role in the management of metastatic colorectal cancer. It allows for the accurate assessment of tumor size, location, and involvement of adjacent structures, which aids in planning the surgical approach. Molecular markers, such as KRAS and BRAF mutations, have emerged as powerful tools in predicting the response to specific therapies and guiding treatment decisions. Neoadjuvant therapy, which involves the administration of chemotherapy or radiation before surgery, has shown promising results in shrinking tumors and improving survival outcomes. Synchronous colorectal liver metastasis, the presence of colorectal cancer metastases in the liver at the time of diagnosis, requires specialized management strategies. Minimally invasive approaches, such as laparoscopic surgery and robotic-assisted surgery, offer less invasive alternatives to traditional open surgery, with potential benefits in terms of reduced pain, faster recovery, and better cosmetic outcomes.

Immunotherapy has revolutionized the treatment of metastatic colorectal cancer in recent years. It involves the use of immune system-based therapies to target and destroy cancer cells. Targeted therapies, such as EGFR inhibitors and anti-PD-L1 antibodies, are designed to block specific signaling pathways that promote cancer growth and survival. Survivorship is a critical aspect of care for patients with metastatic colorectal cancer. It encompasses a range of interventions, including psychosocial support, nutritional counseling, and rehabilitation, aimed at improving the quality of life and overall well-being of patients.

In conclusion, Contemporary Management of Metastatic Colorectal Cancer: A Precision Medicine Approach provides a comprehensive and up-to-date overview of the current knowledge and treatment strategies for metastatic colorectal cancer. By incorporating pre-operative imaging, molecular markers, neoadjuvant therapy, synchronous colorectal liver metastasis, minimally invasive approaches, immunotherapy, targeted therapies, and survivorship, practitioners can deliver optimal care to patients with this complex disease. This book is a valuable resource for practitioners, cancer researchers, oncologists, graduate students, and members of the biomedical research community who seek to stay informed about the latest advancements in colorectal cancer metastasis treatment.

Weight: 450g
ISBN-13: 9780323917063