Copper in N-Heterocyclic Chemistry

Copper in N-Heterocyclic Chemistry provides an overview of copper-catalyzed synthesis and functionalization of N-heterocyclic compounds, exploring their use in natural products and pharmaceuticals, and C-H activation. It offers troubleshooting protocols and highlights the advantages and limitations of each method.

Format: Paperback / softback
Length: 504 pages
Publication date: 17 November 2020
Publisher: Elsevier Science Publishing Co Inc

Copper in N-Heterocyclic Chemistry is a comprehensive guide that provides an overview of copper-catalyzed synthesis and functionalization of N-heterocyclic compounds, catering to researchers and students engaged in the fields of synthetic organic chemistry and medicinal chemistry. The book delves into the significance of N-heterocyclic compounds as unique structural units in the development of natural products and pharmaceuticals, alongside the remarkable advancements in high atom economic strategies and, more recently, copper-catalyzed C-H activation and its applications in organic synthesis. Readers will find valuable troubleshooting protocols alongside an in-depth exploration of the advantages and limitations of each method discussed. Given the versatile chemical reactivity of copper catalysts, encompassing their accessible oxidation states from 0 to 3, their ability to serve as Lewis acids, oxidizing agents, and catalysts, and their role in facilitating bond formations, this book emerges as an invaluable resource on the topics explored.

Weight: 794g
Dimension: 228 x 153 x 29 (mm)
ISBN-13: 9780128212639