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Patric U. B. Vogel

COVID-19: Search for a vaccine

COVID-19: Search for a vaccine

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This book provides an overview of COVID-19 vaccine technologies, including their principles, strengths, weaknesses, and progress. It also explains important terms such as clinical phases, efficacy, and sterilizing immunity, and presents the approved vaccines and the importance of viral variants.

Format: Paperback / softback
Length: 54 pages
Publication date: 03 December 2022
Publisher: Springer Fachmedien Wiesbaden


This comprehensive book delves into the realm of vaccine technologies against the formidable COVID-19 pandemic. It offers a thorough exploration of the principles, strengths, weaknesses, and advancements in various vaccine platforms. Moreover, it elucidates essential terms such as clinical phases, efficacy, and sterilizing immunity, providing a clear understanding of the vaccine development process.

In its second edition, this publication not only presents the already approved vaccines but also emphasizes the significance of viral variants in shaping the pandemic's trajectory. By providing a comprehensive and up-to-date account of vaccine technologies, this book serves as a valuable resource for healthcare professionals, researchers, policymakers, and individuals seeking information and guidance in the fight against COVID-19.

The book begins by introducing the concept of vaccines and their role in preventing infectious diseases. It then delves into the specific challenges posed by COVID-19, including the rapid mutation of the virus and the need for efficient and durable vaccines.

The book proceeds to showcase the progress made in vaccine development against COVID-19. It discusses the different vaccine technologies employed, such as mRNA vaccines, viral vector vaccines, and inactivated vaccines, and their respective advantages and disadvantages. Each vaccine technology is thoroughly examined, including its clinical trials, efficacy, and safety profiles.

Furthermore, the book sheds light on the clinical phases of vaccine development, which involve rigorous testing and evaluation to ensure the safety and efficacy of vaccines before they are approved for widespread use. It explains the criteria used to assess vaccine effectiveness, such as the prevention of severe illness, hospitalization, or death.

The importance of sterilizing immunity is also emphasized, as it provides long-lasting protection against the virus and prevents its spread. The book discusses the different types of sterilizing immunity and the strategies employed to achieve it, including boosting immunity through repeated doses or through combination vaccines.

In addition to presenting the approved vaccines, the book explores the role of viral variants in shaping the pandemic. It discusses the emergence of new variants and their potential impact on vaccine effectiveness. The book provides insights into the strategies used to adapt vaccines to new variants, such as modifying the vaccine composition or adjusting the dosing schedule.

Furthermore, the book addresses the ethical and social considerations surrounding vaccine distribution and uptake. It discusses the challenges faced by different countries in ensuring equitable access to vaccines and mitigating vaccine hesitancy. The book emphasizes the importance of public education and awareness campaigns to promote vaccine acceptance and reduce the spread of misinformation.

In conclusion, this book serves as a comprehensive and authoritative guide to vaccine technologies against COVID-19. It provides a deep understanding of the principles, strengths, and weaknesses of various vaccine platforms, as well as their progress in clinical trials and real-world applications. By presenting the approved vaccines and emphasizing the significance of viral variants, the book equips readers with the knowledge and tools they need to make informed decisions about vaccination. As the pandemic continues to evolve, this book will remain an invaluable resource for healthcare professionals, researchers, policymakers, and individuals seeking to combat COVID-19 and build a safer and healthier future.

Weight: 103g
Dimension: 210 x 148 (mm)
ISBN-13: 9783658389307
Edition number: 1st ed. 2023

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