Current Progress in iPSC-derived Cell Types

The series Advances in Stem Cell Biology is a collection of comprehensive information and new discoveries in stem cell biology. Current Progress in iPSC-derived Cell Types,Volume 10 discusses how induced pluripotent stem cells can be differentiated into different cell types, revolutionizing biomedical research. Written for researchers and scientists, the volume covers advances in stem cell therapy, cell biology, regenerative medicine, and organ transplantation.

Format: Paperback / softback
Length: 336 pages
Publication date: 09 June 2021
Publisher: Elsevier Science Publishing Co Inc

The series Advances in Stem Cell Biology is a timely and comprehensive collection of cutting-edge information and groundbreaking discoveries in the field of stem cell biology. Current Progress in iPSC-derived Cell Types, Volume 10 delves into the fascinating process of differentiating induced pluripotent stem cells into various cell types. By expressing specific transcription factors, somatic cells can be reprogrammed into induced pluripotent stem cells, which have revolutionized biomedical research over the past 15 years. This volume will explore the latest advancements in research aimed at reprogramming induced pluripotent stem cells to develop innovative treatment technologies in regenerative medicine. Authored by esteemed experts in the field, the volume is tailored for researchers and scientists specializing in stem cell therapy, cell biology, regenerative medicine, and organ transplantation.

Introduction:
Stem cell biology has emerged as a pivotal field in modern medicine, offering immense potential for therapeutic advancements and regenerative therapies. Induced pluripotent stem cells (iPSCs) have gained significant attention as a powerful tool in this field due to their ability to differentiate into any cell type and their potential for unlimited replication. In recent years, there has been a growing interest in understanding the mechanisms underlying iPSC differentiation and developing new strategies to harness their therapeutic potential.
Current Progress in iPSC-derived Cell Types:
Current Progress in iPSC-derived Cell Types, Volume 10, edited by renowned experts in the field, provides a comprehensive overview of the latest developments in this area. The volume focuses on the differentiation of iPSCs into different cell types, including neurons, cardiomyocytes, hepatocytes, and osteoblasts. The authors discuss the various protocols and techniques used to induce and maintain iPSC differentiation, as well as the challenges and limitations encountered during the process.
Reprogramming of Somatic Cells into iPSCs:
One of the key aspects of stem cell biology is the ability to reprogram somatic cells into iPSCs. This process involves the expression of specific transcription factors, which induce the cells to adopt a pluripotent state. The reprogramming of somatic cells into iPSCs has opened up new avenues for drug discovery, personalized medicine, and tissue engineering. The volume explores the mechanisms underlying somatic cell reprogramming, including the role of epigenetic regulation, chromatin remodeling, and non-coding RNAs.
Applications of iPSC-derived Cell Types:
iPSC-derived cell types have numerous applications in regenerative medicine and drug discovery. For example, iPSC-derived neurons can be used to study neurological disorders, while iPSC-derived cardiomyocytes can be used to develop new heart therapies. iPSC-derived hepatocytes can be used to model liver diseases and screen potential drugs, while iPSC-derived osteoblasts can be used to repair bone defects. The volume discusses the potential applications of iPSC-derived cell types in various clinical settings and the challenges that need to be addressed to translate these technologies into clinical practice.
Conclusion:
Advances in Stem Cell Biology, Volume 10, serves as a valuable resource for researchers and scientists in stem cell therapy, cell biology, regenerative medicine, and organ transplantation. The volume provides a comprehensive overview of the latest developments in iPSC-derived cell types, reprogramming of somatic cells into iPSCs, and their applications in regenerative medicine. By highlighting the potential of these technologies, the volume encourages further research and development in this field, ultimately leading to improved patient outcomes.

Weight: 702g
Dimension: 189 x 234 x 28 (mm)
ISBN-13: 9780128238844