Degenerative Cervical Myelopathy: From Basic Science to Clinical Practice

Degenerative Cervical Myelopathy: From Basic Science to Clinical Practice is a comprehensive book that covers the latest research, patient management strategies, and promising neuroprotective therapies for DCM. Written by international experts, it helps readers understand the challenges and future directions of patient management.

Format: Hardback
Length: 275 pages
Publication date: 01 August 2023
Publisher: Elsevier Science & Technology

Degenerative Cervical Myelopathy: From Basic Science to Clinical Practice is a comprehensive guide that provides a deep understanding of the manifestation, pathophysiology, diagnosis, and treatment strategies of degenerative cervical myelopathy (DCM). This essential book encompasses the latest basic and clinical research, offering valuable updates on patient management approaches. It also delves into promising neuroprotective therapies that hold the potential for improving the future of DCM care. Written by esteemed international experts across various fields related to DCM, this text aims to assist readers in navigating the complexities and emerging trends in patient management.

Degenerative cervical myelopathy (DCM) is a significant spinal cord dysfunction condition that affects a large number of individuals worldwide. It encompasses a group of chronic, non-traumatic spinal cord injuries caused by degenerative changes in the cervical spine, such as disc spondylosis or repetitive dynamic injury from hyper-mobility. DCM presents with various symptoms, including weakness, numbness, and pain in the arms, hands, and legs, which can significantly impact a person's quality of life.

The pathophysiology of DCM involves a combination of factors, including spinal cord compression, inflammation, and neurodegeneration. As the cervical spine degenerates, the vertebral discs and ligaments lose their flexibility and strength, leading to narrowing of the spinal canal and compression of the spinal cord. This compression can cause damage to the nerve fibers, resulting in neurological deficits and symptoms.

Diagnosing DCM is a complex process that involves a combination of clinical examination, imaging studies, and neurological testing. Magnetic resonance imaging (MRI) is the most commonly used imaging technique to visualize the spinal cord and detect any abnormalities. Other imaging modalities, such as computed tomography (CT) and X-ray, may also be used to assess the spinal anatomy and rule out other potential causes of symptoms.

Treatment for DCM aims to relieve symptoms, improve mobility, and prevent further progression of the disease. Non-surgical treatments, such as physical therapy, medication management, and lifestyle modifications, can be effective in managing symptoms and improving quality of life. In some cases, surgical interventions may be necessary to relieve compression and improve spinal stability. These interventions can include decompression surgery, fusion surgery, or implantation of a spinal cord stimulator.

Research and development in the field of DCM are ongoing, with a focus on identifying new therapies and improving existing treatment options. Promising neuroprotective therapies, such as stem cell therapy and gene therapy, are being studied to slow down the progression of neurodegeneration and potentially restore lost neurological function.

In conclusion, Degenerative Cervical Myelopathy: From Basic Science to Clinical Practice is a vital resource for healthcare professionals, researchers, and individuals affected by DCM. It provides a comprehensive understanding of the disease's manifestation, pathophysiology, diagnosis, and treatment strategies. By staying up-to-date with the latest research and advancements, healthcare providers can offer the best possible care to patients with DCM and improve their quality of life.

Dimension: 276 x 215 (mm)
ISBN-13: 9780323953344