DNA Damage and Double Strand Breaks

The Enzymes series,DNA Damage and Double Strand Breaks,Volume 51, highlights new advances in the field, including female and male genital schistosomiasis, vertebrates as uninfected disseminators, and combatting anthelmintic resistance in ruminants.

Format: Hardback
Length: 164 pages
Publication date: 01 October 2022
Publisher: Elsevier Science & Technology

The Enzymes series, Volume 51, DNA Damage and Double Strand Breaks, is a comprehensive resource that delves into the latest developments in this field. This new volume presents captivating chapters that offer a timely update on female and male genital schistosomiasis, emphasizing the need for integrated efforts to enhance diagnosis, treatment, and awareness in both endemic and non-endemic settings. Additionally, it sheds light on the role of vertebrates as uninfected disseminators of helminth eggs and larvae, highlighting the importance of combating anthelmintic resistance in ruminants.

Female genital schistosomiasis, a neglected tropical disease that affects millions of women worldwide, continues to be a significant public health concern. The chapter on this topic provides an overview of the disease's epidemiology, clinical manifestations, and treatment options, highlighting the need for improved diagnostic tools and targeted interventions. Male genital schistosomiasis, although less prevalent, also poses a significant health risk, particularly in sub-Saharan Africa. The chapter on this subject explores the clinical presentation, diagnosis, and treatment of male schistosomiasis, emphasizing the importance of integrated care and community engagement.

Vertebrates, including fish, reptiles, and mammals, play a crucial role in the transmission of helminth infections. The chapter on vertebrate hosts of helminths highlights the importance of understanding their biology, behavior, and role in disease transmission. It also discusses the challenges associated with controlling helminth infections in vertebrate hosts, including the development of anthelmintic resistance.

Anthelmintic resistance in ruminants, a major concern in animal agriculture, is also addressed in the volume. The chapter explores the mechanisms of anthelmintic resistance, the impact of resistance on livestock productivity, and the strategies employed to combat resistance. It emphasizes the need for sustainable anthelmintic management practices and the development of new anthelmintic agents to maintain the effectiveness of livestock production.

In conclusion, DNA Damage and Double Strand Breaks, Volume 51 in The Enzymes series, provides a valuable resource for researchers, healthcare professionals, and policymakers interested in advancing our understanding of DNA damage and its implications in various biological contexts. The chapters presented in this volume offer insightful perspectives on female and male genital schistosomiasis, vertebrate hosts of helminths, anthelmintic resistance in ruminants, and other relevant topics. By integrating efforts and fostering collaboration, we can work towards improving diagnosis, treatment, and awareness of these diseases, ultimately reducing their global impact.

Dimension: 229 x 152 (mm)
ISBN-13: 9780323993975