Droplets of Life: Membrane-Less Organelles, Biomolecular Condensates, and Biological Liquid-Liquid Phase Separation

Droplets of Life: Membrane-Less Organelles, Biomolecular Condensates, and Biological Liquid–Liquid Phase Separation is a comprehensive book that provides an overview of membrane-less organelles, biomolecular condensates, and biological liquid-liquid phase separation. It explores their biophysics, biogenesis, structure, functions, and roles in living organisms, with contributions from international experts.

Format: Paperback / softback
Length: 728 pages
Publication date: 11 November 2022
Publisher: Elsevier Science Publishing Co Inc

Droplets of Life: Membrane-Less Organelles, Biomolecular Condensates, and Biological Liquid-Liquid Phase Separation is a comprehensive guide that delves into the intricate world of membrane-less organelles, biomolecular condensates, and biological liquid-liquid phase separation. It serves as a foundational resource for understanding the biophysics, biogenesis, structure, functions, and roles of these remarkable cellular components.

The study of liquid-liquid phase separation has garnered significant attention from various disciplines, including cell biology, biophysics, biochemistry, and more. Researchers are eager to unravel the mysteries behind these condensates and their profound impact on homeostasis and disease states in living organisms. This book, edited by a team of international experts, aims to provide a current and authoritative overview of all aspects related to this exciting field.

Sections in the book introduce membrane-less organelles (MLOs) and biomolecular condensates, exploring their diverse sizes, shapes, and compositions. It sheds light on the formation of MLOs through phase separation processes and how these condensates can tune reactions, organize the intracellular environment, and contribute to cellular fitness.

Furthermore, the book delves into the roles of MLOs in various cellular processes, such as protein synthesis, lipid metabolism, and cell signaling. It discusses the mechanisms by which MLOs interact with other organelles and the cellular machinery to maintain cellular homeostasis.

Moreover, the book explores the potential applications of MLOs in drug discovery, biotechnology, and medicine. It discusses the use of MLOs as drug delivery vehicles, biomaterials, and tools for studying cellular processes.

In conclusion, Droplets of Life: Membrane-Less Organelles, Biomolecular Condensates, and Biological Liquid-Liquid Phase Separation is an essential resource for researchers, students, and professionals interested in gaining a deeper understanding of these fascinating cellular components. It provides a comprehensive and up-to-date overview of their biophysics, biogenesis, structure, functions, and roles, paving the way for future advancements in the field.

Weight: 1502g
Dimension: 193 x 236 x 41 (mm)
ISBN-13: 9780128239674