Drug Delivery with Targeted Nanoparticles: In Vitro and In Vivo Evaluation Methods

Nanotechnology-based drug delivery systems offer controlled delivery, improved solubility, and reduced side effects, but few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted. This book discusses the production, characterization, regulation, and currently marketed targeted nanoparticle systems.

Format: Hardback
Length: 762 pages
Publication date: 30 November 2021
Publisher: Jenny Stanford Publishing

Nanotechnology holds immense potential to transform every aspect of our lives. Today, numerous applications utilize nanotechnology-based products, with drug delivery being one of the most significant domains. Nanoparticulate drug delivery systems offer a multitude of advantages, including precise drug release, enhanced drug solubility, improved drug efficiency, and reduced side effects through targeted mechanisms. In contrast to conventional drug delivery systems, few nanoparticle-based products are currently available on the market, and the majority of these are either nontargeted or possess only passive targeting capabilities. Furthermore, the development of targeted nanoparticle systems is a complex and intricate process that necessitates the implementation of various evaluation mechanisms.

This comprehensive book delves into the production, characterization, regulation, and currently marketed targeted nanoparticle systems within a broad framework. It provides an overview of targeted nanoparticles, encompassing their in vitro characterization, including particle size, stability, ligand density, and type. Additionally, it explores their in vivo behavior for different targeting areas, such as tumors, the brain, and the vagina. Furthermore, the book highlights recent advancements in this field, including clinical trials and regulatory processes.

By unraveling the complexities of targeted nanoparticle systems, this book aims to shed light on their immense potential in improving healthcare outcomes and enhancing the quality of life for individuals suffering from various diseases. It serves as a valuable resource for researchers, scientists, healthcare professionals, and policymakers alike, as it offers a comprehensive understanding of this rapidly evolving field.

Weight: 1620g
Dimension: 229 x 152 (mm)
ISBN-13: 9789814877756