Drug Targets in Cellular Processes of Cancer: From Nonclinical to Preclinical Models

This book explores potential cellular drug targets for cancer therapy, discussing conventional treatment and detection strategies, the role of cyclin-dependent kinases and cell cycle regulatory proteins, chemotherapeutic drug regulation, autophagic cell death, ROS species, anti-inflammatory routes, and therapeutic strategies targeting the tumor microenvironment and angiogenic pathways. It is a valuable resource for oncologists, cancer researchers, clinicians, and pharmaceutical industry personnel.

Format: Paperback / softback
Length: 228 pages
Publication date: 02 October 2021
Publisher: Springer Verlag, Singapore

This comprehensive book delves into the realm of potential cellular drug targets for cancer therapy, offering a comprehensive exploration of various treatment approaches and detection methods. The initial chapters provide an in-depth overview of conventional cancer treatments, including radiotherapy, chemotherapy, and immunotherapy, along with the utilization of biosensors for accurate detection. In contrast, the subsequent chapters delve into the intricate mechanisms underlying cancer cell growth, focusing on the role of cyclin-dependent kinases and cell cycle regulatory proteins as potential targets for cancer treatment. The book further explores the regulation of pro-apoptotic and anti-apoptotic proteins through chemotherapeutic drugs, shedding light on the molecular pathways critical for mediating autophagic cell death in cancer cells. Additionally, it examines the role of reactive oxygen species (ROS) during carcinogenesis and chemotherapy, highlighting their potential as therapeutic targets. Furthermore, the book explores innovative therapeutic strategies that target the tumor microenvironment and various angiogenic pathways, aiming to develop personalized medicine approaches for cancer treatment. Given its extensive coverage, this book serves as a valuable resource for oncologists, cancer researchers, clinicians, and pharmaceutical industry professionals, providing valuable insights into the latest advancements in cancer therapy.

Weight: 379g
Dimension: 235 x 155 (mm)
ISBN-13: 9789811575884
Edition number: 1st ed. 2020