Engineering and Physical Approaches to Cancer

Engineering and Physical Approaches to Cancer focuses on the latest research at the interface of cancer biology and the physical sciences, covering topics such as collective and individual cell migration, the tumor microenvironment, and circulating tumor cells. The book is designed for a general audience, including researchers, medical professionals, and trainees, and will be of interest to the pharmaceutical and biomedical device industry.

Format: Hardback
Length: 331 pages
Publication date: 12 April 2023
Publisher: Springer International Publishing AG

Engineering and Physical Approaches to Cancer delves into the cutting-edge research at the intersection of cancer biology and the physical sciences. This comprehensive volume explores various aspects of cancer, including collective and individual cell migration, the crosstalk of biological, chemical, and physical cues in the tumor microenvironment, circulating tumor cells, and metastatic colonization.

Chapters in the book address the mechanobiology of collective and individual cell migration, offering experimental, theoretical, and computational perspectives. These chapters shed light on the mechanisms underlying cell movement within tumors, including the role of cellular adhesion molecules, cytoskeletal dynamics, and molecular motors.

Furthermore, the book delves into the crosstalk of biological, chemical, and physical cues in the tumor microenvironment. It examines the role of senescence, polyploid giant cells, TGF-beta, metabolism, and immune cells in shaping the tumor environment and influencing cancer progression. Chapters also explore the mechanisms by which these factors interact and contribute to tumor growth and metastasis.

In addition, the book focuses on circulating tumor cells and metastatic colonization, highlighting both bioengineered models and diagnostic technologies. It discusses the development of engineered models to study tumor cell behavior and the application of diagnostic tools to detect and monitor cancer cells in the bloodstream.

Furthermore, this book showcases the work of emerging and diverse investigators in the field of physical aspects of cancer. These investigators have made impressive cross-disciplinary scientific contributions, advancing our understanding of cancer biology and paving the way for new therapeutic approaches.

The book is designed for a general audience, particularly researchers conversant in cancer biology but less familiar with engineering (and vice-versa). It provides a comprehensive introduction to the physical aspects of cancer, making it suitable for faculty, postdoctoral fellows, advanced graduate students, and medical professionals. The interdisciplinary nature of the content makes it valuable for researchers in biological sciences, engineering, and the pharmaceutical and biomedical device industry.

Overall, Engineering and Physical Approaches to Cancer is a valuable resource for anyone interested in understanding the physical aspects of cancer and the potential for engineering and physical approaches to cancer treatment and prevention.

Weight: 676g
Dimension: 235 x 155 (mm)
ISBN-13: 9783031228018
Edition number: 1st ed. 2023