Shulph Ink
Epitranscriptomics
Epitranscriptomics
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- More about Epitranscriptomics
Epitranscriptomics is a novel area of cellular and molecular biology that focuses on changes in an organism's cells resulting from the posttranscriptional modification of cellular RNA. RNA-binding proteins (RBPs) play a crucial role in these modifications and support several cellular processes. This book explores the mechanisms underlying RNA modifications and RBP function, revealing that the RNA molecule is not just an information-carrying molecule. It discusses the location, percentage, and impact of posttranscriptional RNA modifications on the genome and their role in various diseases.
Format: Hardback
Length: 632 pages
Publication date: 30 July 2021
Publisher: Springer Nature Switzerland AG
Epitranscriptomics is a novel and exciting field of cellular and molecular biology that focuses on changes in an organism's cells resulting from the posttranscriptional modification of cellular RNA. RNA-binding proteins (RBPs) play a crucial role in these posttranscriptional modifications and also support several cellular processes necessary for maintaining RNA homeostasis. Exploring the mechanisms underlying RNA modifications and RBP function is an emerging area of biomedical research, taking the study of gene regulation a step beyond epigenetics.
This book reveals that the RNA molecule is not just an information-carrying molecule with some secondary structures. Accordingly, how RNA is modified, regulated, packaged, and controlled is an important aspect. Leading experts address questions such as where the over 170 distinct posttranscriptional RNA modifications are located on the genome, what percentage of mRNAs and noncoding RNAs these modifications include, and how an RNA modification impacts a person's biology. In closing, the book reviews the role of RNA modifications and RBPs in a variety of diseases and their pathogenesis.
Addressing some of the most exciting challenges in epitranscriptomics, this book provides a valuable and engaging resource for researchers in academia and industry studying the phenomena of RNA modification.
Weight: 1124g
Dimension: 235 x 155 (mm)
ISBN-13: 9783030716110
Edition number: 1st ed. 2021
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