Foundations of Colorectal Cancer

The book Foundations of Colorectal Cancer is a comprehensive resource that covers all aspects of colorectal cancer, from its demographic and ethical facts to its treatment process, varieties, and genetic background. Written by experts from diverse fields, it brings real-world experiences to help readers with challenges in dealing with patients or during their research workflow.

Format: Paperback / softback
Length: 670 pages
Publication date: 28 October 2021
Publisher: Elsevier Science & Technology

Colorectal cancer is a complex disease that requires a multidisciplinary approach to its study and treatment. Foundations of Colorectal Cancer provides a comprehensive and holistic exploration of this disease, covering the contributions of various disciplines involved in its research and management. Written by experts from diverse fields such as cancer research, oncology, genetics, biochemistry, psychology, social sciences, bioinformatics, and palliative care, the book offers a deep understanding of colorectal cancer from various perspectives.

The content is organized into nine sections, each addressing different aspects of colorectal cancer. The first section, Clinical Manifestations and Disease Detection, explores the clinical manifestations of the disease, including its symptoms, screening methods, and primary and secondary prevention strategies. It also discusses the role of primary care providers in the early detection and management of colorectal cancer.

The second section, Diagnosis and Staging, delves into the diagnostic processes used to identify and stage colorectal cancer. It covers endoscopy, colonoscopy, molecular pathology, and anatomopathological diagnosis, as well as the role of imaging techniques in the evaluation of the disease.

The third section, Treatment, discusses the various treatment options available for colorectal cancer, including endoscopic procedures, surgical interventions, radiological therapies, and postoperative care. It also explores the molecular and biological mechanisms underlying colorectal cancer and the role of intestinal microbiota, stem cells, and signaling pathways in its development and progression.

The fourth section, Molecular and Biological Mechanisms, explores the molecular and biological factors that contribute to colorectal cancer development and progression. It discusses the role of genetic mutations, epigenetic modifications, and environmental factors in the onset and progression of the disease.

The fifth section, New Diagnostic Methods, introduces biomarkers and bioinformatics tools that are used in colorectal cancer research. It discusses the advantages and limitations of these methods and their potential applications in personalized medicine and early detection of the disease.

The sixth section, Biobanks, provides an overview of biobanks and their importance in colorectal cancer research. It discusses the regulations and ethical considerations associated with collecting and storing biological samples and the potential benefits of using these resources in clinical practice and research.

The seventh section, Epidemiological Studies, focuses on the global incidence and mortality of colorectal cancer, as well as regional differences in its prevalence. It explores the risk factors, screening strategies, and treatment outcomes associated with colorectal cancer in different populations.

The eighth section, Hereditary Colorectal Cancer, distinguishes between nonpolyposis and polyposis types of colorectal cancer and discusses the genetic factors that contribute to their development. It also explores the screening and management strategies for individuals with hereditary colorectal cancer.

The ninth section, Addressing the Consequences of Colorectal Cancer, addresses the psychological effects, nutritional considerations, and ethical issues that arise in the context of colorectal cancer. It discusses the importance of support and counseling for patients and their families, as well as the role of palliative care in managing symptoms and improving quality of life.

In conclusion, Foundations of Colorectal Cancer is an essential resource for healthcare professionals, researchers, and individuals interested in understanding and managing colorectal cancer. It provides a comprehensive and up-to-date overview of the disease, covering its clinical manifestations, diagnostic processes, treatment options, molecular and biological mechanisms, and various aspects of research and management. By bringing together experts from diverse fields, the book offers a multidisciplinary perspective on colorectal cancer, enabling readers to gain a deeper understanding of this complex disease and develop effective strategies for its prevention, diagnosis, and treatment.

Weight: 1794g
Dimension: 217 x 276 x 38 (mm)
ISBN-13: 9780323900553