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Genome Stability: From Virus to Human Application
Genome Stability: From Virus to Human Application
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- More about Genome Stability: From Virus to Human Application
The book "Genome Stability: From Virus to Human Application, Second Edition" explores how different species maintain genome stability and diversity in response to environmental factors. It examines epigenetic factors, DNA repair mechanisms, chromatin, and human diseases related to genome instability. The second edition has been updated to include emerging research trends, such as CRISPR/Cas9 genome editing, and is a valuable resource for geneticists, epigeneticists, and molecular biologists.
Format: Paperback / softback
Length: 760 pages
Publication date: 22 July 2021
Publisher: Elsevier Science & Technology
Genome Stability: From Virus to Human Application, Second Edition, a volume in the Translational Epigenetics series, delves into the intricate mechanisms employed by diverse species to maintain genome stability and facilitate genome diversification in response to environmental cues. Spanning thirty-eight chapters, esteemed researchers offer a comprehensive examination of genome stability across DNA/RNA viruses, prokaryotes, single-cell eukaryotes, lower multicellular eukaryotes, and mammals. Through in-depth analysis, they explore how epigenetic factors contribute to genome stability and how these species transmit memories of encounters to their progeny. The book also delves into major DNA repair mechanisms, the role of chromatin in genome stability, human diseases linked to genome instability, and the preservation of genome stability amidst aging. This second edition has undergone a thorough revision to incorporate emerging research trends, such as CRISPRs/Cas9 genome editing, conventional versus transgenic genome instability, breeding and genetic disorders associated with abnormal DNA repair, RNA and extrachromosomal DNA, cloning, stem cells, and embryo development, programmed genome instability, and conserved and divergent features of repair. This comprehensive volume serves as a vital resource for geneticists, epigeneticists, and molecular biologists seeking to deepen their understanding of this rapidly evolving field, while also being invaluable to advanced students seeking to expand their expertise in genome stability.
Weight: 2040g
Dimension: 235 x 191 (mm)
ISBN-13: 9780323856799
Edition number: 2 ed
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