Glycobiology of Innate Immunology

The book provides the latest knowledge and research results on glycobiology of innate immunology, which plays a crucial role in human diseases and microbial invasions. It discusses the co-regulated expression of glycan-binding and its association with biological components such as cellular oncotransformation, phenotype change, neuronal or embryonic development, and intracellular signaling.

Format: Hardback
Length: 656 pages
Publication date: 01 April 2022
Publisher: Springer Verlag, Singapore

This comprehensive book delves into the latest knowledge and cutting-edge research findings in the field of glycobiology, specifically focusing on its implications in innate immunology. Innate immunity, a vital component of the immune system, plays a crucial role in defending the body against a wide range of threats, including microbial invaders and self-associated molecular patterns. Glycans, the complex sugar molecules found on the surface of cells and proteins, play a pivotal role in innate immunity by facilitating interactions between immune cells and their targets.

The book begins by providing a foundational understanding of glycans in innate immunity, including their structure, synthesis, and function. It then explores in depth the intricate mechanisms behind Dendritic cell interactions during infection and inflammation. The authors examine the role of glycans in regulating immune responses, such as cytokine production and T cell activation, and discuss the implications of these interactions in disease development.

In the subsequent chapters, the book provides up-to-date information on all aspects of glycan structure-recognizing signaling. It discusses the role of glycans in mediating immune cell communication, pathogen recognition, and the development of immune tolerance. The authors explore the diverse functions of glycan-binding proteins, such as lectins and antibodies, and their involvement in immune surveillance and immune regulation.

Furthermore, the book delves into the therapeutic potential of glycans in immune-based therapies. It discusses the use of glycan-modifying enzymes and glycan-based vaccines as tools for treating infectious diseases and cancer. The authors explore the challenges and opportunities associated with these approaches and provide insights into the future directions of glycobiology research.

Overall, this book serves as a valuable resource for researchers, clinicians, and students interested in glycobiology and innate immunity. It provides a comprehensive and up-to-date overview of the field, covering both basic and advanced topics, and serves as a foundation for further research and development in this area.

Weight: 1172g
Dimension: 235 x 155 (mm)
ISBN-13: 9789811690808
Edition number: 1st ed. 2022