Halogen Bonding in Solution

Halogen bonding (XB) is an important interaction between an electron donor and the electrophilic region of a halogen atom that has been largely overlooked in solution. This book provides a concise overview of halogen bond interactions in solution, discussing their history, electronic origin, and applications in organocatalysis, industrial applications, anion transport, and binding. It is aimed at facilitating exciting future developments in the field and is a valuable resource for researchers and professionals working in supramolecular chemistry, catalysis, biochemistry, drug design, and electrochemistry.

\n Format: Hardback
\n Length: 416 pages
\n Publication date: 03 February 2021
\n Publisher: Wiley-VCH Verlag GmbH
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Halogen bonding (XB) is a fascinating chemical interaction that has gained significant attention in recent years due to its importance in various fields, including synthesis, catalysis, biochemistry, and electrochemistry. This bond type involves the transfer of an electron from an electron donor to the electrophilic region of a halogen atom, resulting in the formation of a stable bond. While halogen bonding has been studied in solid state for decades, its potential in solution has only recently been recognized.

The significance of halogen bonding in solution lies in the fact that most physiological processes and chemical reactions occur in this medium. Therefore, investigations into halogen bond interactions in solution hold immense relevance for its application in organic synthesis and catalysis, pharmaceutical chemistry and drug design, electrochemistry, as well as material synthesis.

Halogen Bonding in Solution provides a comprehensive overview of halogen bond interactions in solution. It discusses the historical background and electronic origins of halogen bonding, highlighting its unique properties and characteristics. The book also summarizes various examples of halogen bonding applications in organocatalysis, including the use of molecular iodine in catalysis and industrial processes. Additionally, it explores recent developments in anion transport and binding, further expanding the scope of halogen bonding in solution.

One of the key advantages of halogen bonding in solution is its ability to facilitate complex molecular recognition processes. Halogen atoms, being electronegative, can form strong bonds with electron-deficient molecules, such as oxygen, nitrogen, and sulfur. This property makes halogen bonding particularly useful in drug discovery, where it can be employed to design and develop novel therapeutic agents with improved potency and selectivity.

In addition to its applications in drug discovery, halogen bonding has found significant use in catalysis. Halogen-containing catalysts, such as Grubbs' catalysts, have been widely used in organic synthesis for the production of various organic compounds. These catalysts utilize halogen bond interactions to promote selective reactions and improve the efficiency of chemical transformations.

Halogen bonding also plays a crucial role in biochemistry and electrochemistry. For instance, it is involved in the formation of protein-halogen bonds, which are essential for the proper functioning of many biological processes. Halogen bonding also contributes to the electrochemical properties of halogen-containing compounds, such as halides and perhalogenated compounds, which are used in various industrial applications, including electronics and energy storage.

Overall, Halogen Bonding in Solution is a valuable resource for researchers and practitioners in the fields of chemistry, biochemistry, and electrochemistry. It provides a comprehensive overview of halogen bond interactions in solution, highlighting its unique properties and applications. The book is aimed at facilitating exciting future developments in the field by providing a comprehensive understanding of halogen bonding and its potential for addressing complex scientific challenges.

\n Weight: 918g\n
Dimension: 179 x 250 x 26 (mm)\n
ISBN-13: 9783527347315\n \n