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Douglas Fullen,May P. Chan,Aleodor A. Andea,David P. Arps

Handbook of Direct Immunofluorescence: A Pattern-Based Approach to Skin and Mucosal Biopsies

Handbook of Direct Immunofluorescence: A Pattern-Based Approach to Skin and Mucosal Biopsies

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  • More about Handbook of Direct Immunofluorescence: A Pattern-Based Approach to Skin and Mucosal Biopsies


Immunofluorescence is a crucial diagnostic tool in dermatopathology, and interpreting the results requires skill. Handbook of Direct Immunofluorescence provides practical, clinically oriented coverage of day-to-day findings, less common patterns, and rarities, with images and information on diagnostic pitfalls. It is a valuable resource for dermato-, oral, and general pathologists, as well as dermatologists.

Format: Hardback
Length: 192 pages
Publication date: 18 March 2018
Publisher: JP Medical Ltd


Immunofluorescence plays a vital role in dermatopathology, serving as a crucial diagnostic tool for a wide range of cutaneous disorders. Its significance lies in its ability to detect and characterize immune cells and proteins in the skin, providing valuable insights into the underlying pathology of connective tissue diseases, vasculitis, and other cutaneous conditions.

Interpreting the results of immunofluorescence testing and correlating them with histopathological findings is a critical skill that requires expertise not only of dermatopathologists but also of dermatologists who either review the slides themselves or rely on pathology labs or academic referral centers. This interdisciplinary collaboration is essential for accurate diagnosis and proper management of these disorders.

Handbook of Direct Immunofluorescence is a comprehensive resource that addresses both day-to-day findings and less common patterns and rarities in immunofluorescence. It provides detailed information on important diagnostic pitfalls and offers practical guidance for dermatologists, oral and general pathologists, and trainees alike.

The book is organized into chapters dedicated to specific diseases, each introduced by concise text that outlines the clinical presentation and pathogenesis of the condition. This clinical context helps readers understand the relevance of immunofluorescence findings in diagnosing and managing these diseases.

Following the introductory text, multiple images showcase the range of histopathological and immunofluorescence findings associated with each disease. These images, accompanied by detailed captions, allow readers to visualize the various patterns and characteristics that can aid in the diagnosis process.

One of the key strengths of Handbook of Direct Immunofluorescence is its practical, clinically oriented coverage. The book provides invaluable insights into technical aspects such as specimen procurement, transportation, and interpretation, ensuring that readers have a comprehensive understanding of the entire immunofluorescence testing process.

Furthermore, the book adopts a pattern-based approach to diagnosis, which serves as a logical framework for reaching a definitive diagnosis and understanding when to order additional tests or consider nonspecific findings. This approach helps practitioners streamline the diagnostic workflow and make informed decisions based on the available evidence.

In conclusion, Handbook of Direct Immunofluorescence is a must-have resource for dermatologists, pathologists, and trainees seeking to enhance their understanding and proficiency in immunofluorescence. Its comprehensive coverage, practical insights, and pattern-based approach make it an invaluable tool in diagnosing and managing cutaneous disorders. By leveraging the power of immunofluorescence, practitioners can improve patient outcomes and deliver the highest level of care to their patients.

Weight: 540g
Dimension: 178 x 247 x 15 (mm)
ISBN-13: 9781907816901

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