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Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 1: Principles and Practice of Toxicologic Pathology

Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 1: Principles and Practice of Toxicologic Pathology

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  • More about Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 1: Principles and Practice of Toxicologic Pathology


The Handbook of Toxicologic Pathology, recognized as the most authoritative source in toxicologic pathology, has been extensively updated to four separate volumes. Volume 1 covers Principles and Practice, Volume 2 encompasses Safety Assessment and Environmental Toxicologic Pathology, and Volumes 3 and 4 provide comprehensive treatment of Target Organ Toxicity. These volumes are essential for pathologists, toxicologists, research scientists, and regulators studying drugs, biologics, medical devices, and other chemicals.

Format: Hardback
Length: 1152 pages
Publication date: 10 January 2022
Publisher: Elsevier Science Publishing Co Inc


The Handbook of Toxicologic Pathology, authored by Haschek and Rousseaux, is widely regarded as the most authoritative and comprehensive reference in the field of toxicologic pathology. Recognizing the rapid advancements in this field, the fourth edition has been expanded into four separate volumes to ensure comprehensive and timely coverage.

Volume 1, Principles and the Practice of Toxicologic Pathology, comprises three parts. The first part, Principles of Toxicologic Pathology, delves into the fundamental principles and concepts of toxicologic pathology. The second part, Methods in Toxicologic Pathology, provides detailed protocols and techniques for conducting toxicologic pathology examinations. The third part, the Practice of Toxicologic Pathology, showcases the practical application of toxicologic pathology in various settings.

In addition to these core volumes, the Handbook encompasses two other volumes. Volume 2, Toxicologic Pathology in Safety Assessment and Environmental Toxicologic Pathology, focuses on the application of toxicologic pathology in safety assessment and environmental toxicology. It covers topics such as the development of specific product classes, principles of data interpretation for safety assessment, and toxicologic pathology of major classes of environmental toxicants.

Volumes 3 and 4, Target Organ Toxicity and Mechanisms of Toxicity, provide in-depth and comprehensive treatment of target organ toxicity. These volumes emphasize the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. They serve as the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators involved in studying and making decisions regarding drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants.

To facilitate access and convenience, each volume in the Handbook is being published separately. This allows readers to focus on specific areas of interest or need, making it an invaluable resource for professionals in the field.

In conclusion, the Handbook of Toxicologic Pathology, with its extensive updates and expanded coverage, remains the gold standard in toxicologic pathology. Its comprehensive and timely content makes it an essential tool for pathologists, toxicologists, research scientists, and regulators seeking to stay abreast of the latest developments and advancements in this field.

Weight: 3150g
Dimension: 276 x 216 (mm)
ISBN-13: 9780128210444
Edition number: 4 ed

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