Heart of the Matter: Key concepts in cardiovascular science

This textbook covers the scientific basics of cardiovascular medicine and biology, including developmental, cellular, and molecular aspects, as well as cardiovascular diseases and therapies. Written by lecturers from Imperial College London, it is a valuable guide for medical students and students in cardiovascular biomedicine.

Format: Paperback / softback
Length: 236 pages
Publication date: 13 November 2019
Publisher: Springer Nature Switzerland AG

This comprehensive textbook delves into the intricate scientific foundations of cardiovascular medicine and biology, encompassing a wide range of topics. It not only explores the developmental and cellular aspects of normally functioning vasculature and the heart but also delves into the molecular mechanisms underlying these processes. Importantly, it addresses the underlying causes and factors involved in various cardiovascular diseases, providing valuable insights into potential therapeutic targets. While the primary focus lies in novel therapies and emerging therapeutic approaches, the book also addresses controversial topics such as cardiac remodeling and regenerative capacities.

Written by esteemed lecturers from Imperial College London, in collaboration with their students from the Colleges BSc Programme in Medical Sciences with Cardiovascular Science, each chapter in this textbook is a testament to the expertise and knowledge of the authors. By bridging the gap between clinical practice and basic biology, this book serves as an invaluable resource for medical students, as well as for Master and PhD students in Cardiovascular Biomedicine.

The textbook is organized into nine chapters, each dedicated to a specific aspect of cardiovascular medicine and biology. The first chapter provides an introduction to the cardiovascular system, covering its structure, function, and regulation. The subsequent chapters delve into the development and function of blood vessels, the heart, and the mechanisms involved in cardiovascular diseases.

Chapter 2 explores the cellular and molecular mechanisms underlying blood vessel development and function, including the role of growth factors, signaling pathways, and extracellular matrix proteins. Chapter 3 focuses on the structure and function of the heart, including its electrical conduction system, contractile properties, and the regulation of heart rate and rhythm. Chapter 4 discusses the molecular mechanisms underlying heart failure, including the role of genetic factors, inflammation, and cellular stress responses.

Chapter 5 explores the cellular and molecular mechanisms involved in the development and progression of cardiovascular diseases, including atherosclerosis, myocardial infarction, and stroke. Chapter 6 discusses the role of inflammation in cardiovascular diseases, including the mechanisms by which inflammation promotes atherosclerosis, promotes myocardial infarction, and contributes to stroke. Chapter 7 explores the role of genetics in cardiovascular diseases, including the inheritance patterns of common cardiovascular diseases and the potential for genetic therapies.

Chapter 8 discusses the cellular and molecular mechanisms involved in cardiac remodeling and regeneration, including the role of stem cells, growth factors, and extracellular matrix proteins. Chapter 9 discusses the emerging therapies and therapeutic targets for cardiovascular diseases, including gene therapy, cell therapy, and wearable technology.

In conclusion, this textbook offers a comprehensive and up-to-date introduction to the scientific foundations of cardiovascular medicine and biology. By covering a wide range of topics, from developmental and cellular aspects to molecular mechanisms and cardiovascular diseases, it provides valuable insights into potential therapeutic targets and offers a roadmap for future research and clinical practice. Whether you are a medical student, a researcher, or a healthcare professional, this textbook is an essential resource for advancing your understanding of cardiovascular medicine and biology.

Weight: 434g
Dimension: 171 x 242 x 14 (mm)
ISBN-13: 9783030242183
Edition number: 1st ed. 2019