Hormone Receptors: Structures and Functions

Hormone Receptors: Structures and Functions, Volume 123 in the Vitamins and Hormones series, highlights new advances in the field with interesting chapters written by an international board of authors.

Format: Hardback
Length: 686 pages
Publication date: 12 September 2023
Publisher: Elsevier Science Publishing Co Inc

The Vitamins and Hormones series, Volume 123, "Hormone Receptors: Structures and Functions," showcases exciting advancements in the field through its latest publication. This comprehensive volume features captivating chapters authored by a distinguished international panel of experts, providing valuable insights into the latest developments and breakthroughs.

The book delves into the intricate structures and crucial roles of hormone receptors, emphasizing their significance in regulating various physiological processes. It explores the mechanisms by which hormones interact with these receptors, leading to specific cellular responses and ultimately influencing human health and behavior.

Chapter 1 provides an overview of hormone receptors, their classification, and their role in signal transduction. It discusses the different types of hormone receptors, including nuclear receptors, membrane receptors, and G protein-coupled receptors, and highlights their unique characteristics and functions.

Chapter 2 explores the molecular mechanisms underlying hormone receptor activation and regulation. It discusses the binding of hormones to their receptors, the activation of signaling pathways, and the transcriptional regulation of target genes. The chapter also sheds light on the role of hormone receptors in the development and progression of diseases, such as cancer and metabolic disorders.

Chapter 3 focuses on the clinical applications of hormone receptors. It discusses the use of hormone receptor-targeted therapies in the treatment of breast cancer, prostate cancer, and other hormone-dependent diseases. The chapter highlights the advantages and challenges of these therapies, as well as the potential for personalized medicine based on individual hormone receptor profiles.

Chapter 4 explores the role of hormone receptors in the regulation of appetite and energy balance. It discusses the mechanisms by which hormones, such as leptin and ghrelin, interact with their receptors to control food intake and energy expenditure. The chapter also discusses the implications of hormone receptor dysfunction in obesity and related disorders.

Chapter 5 explores the role of hormone receptors in the development and function of the reproductive system. It discusses the mechanisms by which hormones, such as estrogen and progesterone, interact with their receptors to regulate reproductive function and the development of sexual characteristics. The chapter also highlights the importance of hormone receptors in the prevention and treatment of reproductive disorders, such as infertility and menopause.

Chapter 6 explores the role of hormone receptors in the development and function of the nervous system. It discusses the mechanisms by which hormones, such as serotonin and dopamine, interact with their receptors to regulate mood, behavior, and cognitive function. The chapter also highlights the implications of hormone receptor dysfunction in neurological disorders, such as depression and anxiety.

Chapter 7 explores the role of hormone receptors in the development and function of the immune system. It discusses the mechanisms by which hormones, such as cytokines and interleukins, interact with their receptors to regulate immune function and inflammation. The chapter also highlights the implications of hormone receptor dysfunction in immune-related diseases, such as autoimmune disorders and allergies.

Chapter 8 explores the role of hormone receptors in the development and function of the skin. It discusses the mechanisms by which hormones, such as estrogen and testosterone, interact with their receptors to regulate skin growth, differentiation, and function. The chapter also highlights the implications of hormone receptor dysfunction in skin diseases, such as acne and psoriasis.

Chapter 9 explores the role of hormone receptors in the development and function of the heart and blood vessels. It discusses the mechanisms by which hormones, such as angiotensin II and aldosterone, interact with their receptors to regulate blood pressure, heart rate, and vascular function. The chapter also highlights the implications of hormone receptor dysfunction in cardiovascular diseases, such as heart failure and stroke.

Chapter 10 explores the role of hormone receptors in the development and function of the bone and muscle. It discusses the mechanisms by which hormones, such as growth hormone and insulin-like growth factor the factors, interact with their receptors to regulate bone growth, metabolism, and muscle development. The chapter also highlights the implications of hormone receptor dysfunction in bone diseases, such as osteoporosis and muscle weakness.

Chapter 11 explores the role of hormone receptors in the development and function of the pancreas. It discusses the mechanisms by which hormones, such as glucagon and insulin, interact with their receptors to regulate blood sugar function and sugar metabolism. The chapter also highlights the implications of hormone receptor dysfunction in pancreatic diseases, such as diabetes and pancreatitis.

Chapter 12 explores the role of hormone receptors in the development and function of the liver. It discusses the mechanisms by which hormones, such as bile acids and glucagon, interact with their receptors to regulate liver function and bile acid metabolism. The chapter also highlights the implications of hormone receptor dysfunction in liver diseases, such as hepatitis and cirrhosis.

Chapter 13 explores the role of hormone receptors in the development and function of the kidney. It discusses the mechanisms by which hormones, such as angiotensin II and aldosterone, interact with their receptors to regulate blood function and water balance. The chapter also highlights the implications of hormone receptor dysfunction in kidney diseases, such as renal failure and hypertension.

Chapter 14 explores the role of hormone receptors in the development and function of the thyroid gland. It discusses the mechanisms by which hormones, such as thyroxine and triiodothyronine, interact with their receptors to regulate thyroid function and metabolism. The chapter also highlights the implications of hormone receptor dysfunction in thyroid diseases, such as hyperthyroidism and hypothyroidism.

Chapter 15 explores the role of hormone receptors in the development and function of the adrenal gland. It discusses the mechanisms by which hormones, such as cortisol and aldosterone, interact with their receptors to regulate adrenal function and metabolism. The chapter also highlights the implications of hormone receptor dysfunction in adrenal diseases, such as Addison's disease and Cushing's syndrome
The Vitamins and Hormones series, Volume 123, "Hormone Receptors: Structures and Functions," showcases exciting advancements in the field through its latest publication. This comprehensive volume features captivating chapters authored by a distinguished international panel of experts, providing valuable insights into the latest developments and breakthroughs.

The book delves into the intricate structures and crucial roles of hormone receptors, emphasizing their significance in regulating various physiological processes. It explores the mechanisms by which hormones interact with these receptors, leading to specific cellular responses and ultimately influencing human health and behavior.

Chapter 1 provides an overview of hormone receptors, their classification, and their role in signal transduction. It discusses the different types of hormone receptors, including nuclear receptors, membrane receptors, and G protein-coupled receptors, and highlights their unique characteristics and functions.

Chapter 2 explores the molecular mechanisms underlying hormone receptor activation and regulation. It discusses the binding of hormones to their receptors, the activation of signaling pathways. It also sheds light on the role the chapter also sheds light on the role of hormone receptors in the development and progression of diseases, such as cancer and metabolic disorders.

Chapter 3 focuses on the clinical applications of hormone receptors. It discusses the use of hormone receptor-targeted therapies in the treatment of breast cancer, prostate cancer, and other hormone-dependent diseases. The chapter highlights the advantages and challenges of these therapies, as well as the potential for personalized medicine based on individual hormone receptor profiles.

Chapter 4 explores the role of hormone receptors in the regulation of appetite and energy balance. It discusses the mechanisms by which hormones, such as leptin and ghrelin, interact with their receptors to control food intake and energy expenditure. The chapter also discusses the implications of hormone receptor dysfunction in obesity and related disorders.

Chapter 5 explores the role of hormone receptors in the development and function of the reproductive system. It discusses the mechanisms by which hormones, such as estrogen and progesterone, interact with their receptors to regulate reproductive function and the development of sexual characteristics. The chapter also highlights the importance of hormone receptors in the prevention and treatment of reproductive disorders, such as infertility and menopause.

Chapter 6 explores the role of hormone receptors in the development and function of the nervous system. It discusses the mechanisms by which hormones, such as serotonin and dopamine, interact with their receptors to regulate mood, behavior, and cognitive function. The chapter also highlights the implications of hormone receptor dysfunction in neurological disorders, such as depression and anxiety.

Chapter 7 explores the role of hormone receptors in the development and function of the immune system. It discusses the mechanisms by which hormones, such as cytokines and interleukins, interact with their receptors to regulate immune function and inflammation. The chapter also highlights the implications of hormone receptor dysfunction in immune-related diseases, such as autoimmune disorders and allergies.

Chapter 8 explores the role of hormone receptors in the development and function of the skin. It discusses the mechanisms by which hormones, such as estrogen and testosterone, interact with their receptors to regulate skin growth, differentiation, and function. The chapter also highlights the implications of hormone receptor dysfunction in skin diseases, such as acne and psoriasis.

Chapter 9 explores the role of hormone receptors in the development and function of the heart and blood vessels. It discusses the mechanisms by which hormones, such as angiotensin II and aldosterone, interact with their receptors to regulate blood pressure, heart rate, and vascular function. The chapter also highlights the implications of hormone receptor dysfunction in cardiovascular diseases, such as heart failure and stroke.

Chapter 10 explores the role of hormone receptors in the development and function of the bone and muscle. It discusses the mechanisms by which hormones, such as growth hormone and insulin-like growth factors, interact with their receptors to regulate bone growth, metabolism, and muscle development. The chapter also highlights the implications of hormone receptor dysfunction in bone diseases, such as osteoporosis and muscle weakness.

Chapter 11 explores the role of hormone receptors in the development and function of the pancreas. It discusses the mechanisms by which hormones, such as glucagon and insulin, interact with their receptors to regulate blood function and sugar metabolism. The chapter also highlights the implications of hormone receptor dysfunction in pancreatic diseases, such as diabetes and pancreatitis.

Chapter 12 explores the role of hormone receptors in the development and function of the liver. It discusses the mechanisms by which hormones, such as bile acids and glucagon, interact with their receptors to regulate liver function and bile acid metabolism. The chapter also highlights the implications of hormone receptor dysfunction in liver diseases, such as hepatitis and cirrhosis.

Chapter 13 explores the role of hormone receptors in the development and function of the kidney. It discusses the mechanisms by which hormones, such as angiotensin II and aldosterone, interact with their receptors to regulate blood function and water balance. The chapter also highlights the implications of hormone receptor dysfunction in kidney diseases, such as renal failure and hypertension.

Chapter 14 explores the role of hormone receptors in the development and function of the thyroid. It discusses the mechanisms by which hormones, such as thyroxine and triiodothyronine, interact with their receptors to regulate thyroid function and metabolism. The chapter also highlights the implications of hormone receptor dysfunction in thyroid diseases, such as hyperthyroidism and hypothyroidism.

Chapter 15 explores the role of hormone receptors in the development and function of the adrenal. It discusses the mechanisms by which hormones, such as cortisol and aldosterone, interact with their receptors to regulate adrenal function and metabolism. The chapter also highlights the implications of hormone receptor dysfunction in adrenal diseases, such as Addison's disease and Cushing's

Weight: 450g
Dimension: 229 x 151 (mm)
ISBN-13: 9780443134555