Human Genome in Health and Disease: A Story of Four Letters

The Human Genome in Health and Disease: A Story of Four Letters explores the relationship between DNA sequence information and biological function, discussing sequence-based functional units and their medical applications. It is designed for students of genetics, biology, medicine, molecular biology, and bioinformatics, with rich illustrations and review questions.

Format: Paperback / softback
Length: 283 pages
Publication date: 01 February 2019
Publisher: Taylor & Francis Inc

The human genome is a remarkable linear sequence of approximately 3 billion bases, and the amount of information associated with it is rapidly expanding. This remarkable progress has sparked a deep exploration into the intricate relationship between genome sequence and biological function. In response to these advancements, "The Human Genome in Health and Disease: A Story of Four Letters" delves into the profound connection between sequence information and biological processes. The book presents a comprehensive examination of various sequence-based functional units within the genome, highlighting their significance in understanding inherited disorders and cancer. Additionally, it explores valuable medical applications related to human genome sequencing, such as gene therapy methods and the identification of causative mutations in rare genetic disorders.

The primary target audience of this book includes students pursuing studies in genetics, biology, medicine, molecular biology, and bioinformatics. It is designed to provide a solid foundation in genetics and molecular biology, even for those without prior knowledge in these areas. The book is extensively illustrated with review questions for each chapter, aiding in student comprehension and retention of the material. Furthermore, it offers valuable insights to advanced non-academics who are interested in learning more about their genome in the era of personal genomics.

Some of the key selling features of "The Human Genome in Health and Disease: A Story of Four Letters" include:

Molecular Sequence Perspective: The book offers a molecular sequence perspective, elucidating the relationship between DNA sequence motifs and biological function. This approach helps students understand how genetic variations and mutations impact biological processes.

Aids in Understanding the Functional Impact of Mutations and Genetic Variants: By presenting the material at a basic level, the book facilitates a deeper understanding of the functional consequences of genetic variants. It aids in interpreting genetic data and interpreting the role of genes in health and disease.

Accessible to Students without Previous Studies of Genetics and Molecular Biology: The book is written in a clear and concise manner, making it accessible to students with various backgrounds. It provides a solid foundation for those who wish to delve into the field of genetics and molecular biology.

Richly Illustrated with Questions Provided to Each Chapter: The book is richly illustrated with diagrams, figures, and tables to enhance visual understanding of the topics. Additionally, questions provided to each chapter help students test their knowledge and reinforce the learning process.

In conclusion, "The Human Genome in Health and Disease: A Story of Four Letters" is a comprehensive and engaging book that provides students with a solid foundation in genetics and molecular biology. It explores the intimate link between genome sequence and biological function, highlighting the significance of sequence-based functional units in understanding inherited disorders, cancer, and medical applications related to human genome sequencing. With its molecular sequence perspective, accessible language, and rich illustrations, the book is an invaluable resource for students, researchers, and anyone interested in gaining a deeper understanding of the human genome and its role in shaping our lives.

Weight: 836g
Dimension: 275 x 213 x 13 (mm)
ISBN-13: 9780815345916